RecruitingNCT05011045

Neurocognitive Outcomes After Whole Brain Radiation Therapy for Hematologic Malignancies


Sponsor

M.D. Anderson Cancer Center

Enrollment

100 participants

Start Date

Jan 9, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

This study assesses neurocognitive outcomes after receiving radiation therapy to the brain (whole brain radiation therapy) in patients with blood cancers (hematologic malignancies). This may help researchers learn more about the effects of whole brain radiation therapy on memory and thinking in patients with blood cancer.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Age 18 years or older
  • Treatment with radiation therapy to the brain for a hematologic malignancy (ex. primary central nervous system lymphoma \[PCNSL\], secondary central nervous system lymphoma \[SCNSL\], leukemia, myeloma)
  • Proficient and capable of completing tests in English
  • Patients with claustrophobia are eligible if the claustrophobia is managed with medication
  • Patients with cognitively-impairment are eligible if the impairment is managed with medication
  • Patients who are pregnant

Interventions

PROCEDUREMagnetic Resonance Imaging

Undergo MRI

OTHERNeurocognitive Assessment

Undergo neurocognitive function assessment

OTHERQuality-of-Life Assessment

Complete questionnaires

OTHERQuestionnaire Administration

Complete questionnaires


Locations(1)

M D Anderson Cancer Center

Houston, Texas, United States

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NCT05011045


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