RecruitingNCT05697575

Non-immunogenic Staphylokinase in Reperfusion Therapy of Ischemic Stroke in Routine Clinical Practice

Non-interventional Observational Study to Evaluate the Efficacy and Safety of Non-immune Staphylokinase in Reperfusion Therapy of Ischemic Stroke in Routine Clinical Practice


Sponsor

National Society for Neurosonology and Cerebral Circulation

Enrollment

336 participants

Start Date

Feb 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The study will collect data from aged 18 to 85 years with a diagnosis of acute stroke, who received thrombolytic treatment with a new agent, nonimmunogenic staphylokinase. Outcomes will be checked for safety and compared to the results of treatment with the other thrombolytic drug, alteplase.


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Inclusion Criteria3

  • Age 18-85 ;
  • Diagnosis of acute ischemic stroke eligible for thrombolytic therapy;
  • Thrombolytic therapy with the drug "non-immunogenic staphylokinase" is planned or has already been performed.

Exclusion Criteria3

  • Individual intolerance or known hypersensitivity to a recombinant protein containing the amino acid sequence of staphylokinase;
  • The presence of a contraindication to thrombolytic therapy of ischemic stroke;
  • Pregnancy or lactation.

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Locations(1)

St. Petersburg Research Institute of Emergency Medicine named after I.I. Janelidze

Saint Petersburg, Russia

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NCT05697575


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