Acute Stroke Clinical Trials

49 recruitingLast updated: June 18, 2026

There are 49 actively recruiting acute stroke clinical trials across 24 countries. Studies span Not Applicable, Phase 3, Phase 4, Phase 1, Phase 2. Top locations include Islamabad, Pakistan, Minneapolis, Minnesota, United States, Baltimore, Maryland, United States. Updated daily from ClinicalTrials.gov.


Acute Stroke Trials at a Glance

49 actively recruiting trials for acute stroke are listed on ClinicalTrialsFinder across 6 cities in 24 countries. The largest study group is Not Applicable with 27 trials, with the heaviest enrollment activity in Islamabad, Minneapolis, and Baltimore. Lead sponsors running acute stroke studies include Foundation University Islamabad, National Taiwan University Hospital, and Riphah International University.

Browse acute stroke trials by phase

Treatments under study

About Acute Stroke Clinical Trials

Looking for clinical trials for Acute Stroke? There are currently 35 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Acute Stroke trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Acute Stroke clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 49 trials

Recruiting

Continuous Dual Aspiration Technique With Zoom System for Stroke

Acute StrokeIschemic Stroke
Imperative Care, Inc.750 enrolled13 locationsNCT07491952
Recruiting
Not Applicable

Effectiveness of Best Care Practices in Acute Stroke in Conventional Hospitalization (BEST CARE ICTUS_HC)

StrokeCerebrovascular DisordersAcute Stroke+6 more
University of Malaga700 enrolled4 locationsNCT07627399
Recruiting
Not Applicable

Combined Effects of Rhythmic Breathing and Balance Training on Balance and Trunk Control in Stroke Patients

Sub-acute Stroke
Riphah International University50 enrolled1 locationNCT07576166
Recruiting
Phase 2Phase 3

Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)

StrokeAcute StrokeIschemic Stroke
DiaMedica Therapeutics Inc728 enrolled66 locationsNCT05065216
Recruiting
Not Applicable

Sensory-Motor Rehabilitation Post Stroke

Acute Stroke
University of Maryland, Baltimore140 enrolled1 locationNCT02369770
Recruiting

Circulating Non-coding RNA in Acute Ischemic Stroke (AISRNA)

Acute StrokeIschemic Stroke
Nanjing First Hospital, Nanjing Medical University500 enrolled1 locationNCT04175691
Recruiting

Non-immunogenic Staphylokinase in Reperfusion Therapy of Ischemic Stroke in Routine Clinical Practice

Acute Stroke
National Society for Neurosonology and Cerebral Circulation336 enrolled1 locationNCT05697575
Recruiting
Not Applicable

Personalized Music-Enhanced Aerobic Training for Patients in Subacute Stroke Recovery

Subacute stroke
Trịnh Minh Tú92 enrolled1 locationNCT07503522
Recruiting
Phase 3

Optimizing Early Nutrition Support in Severe Stroke-2

severe strokeAcute StrokeDysphagia
Wen Jiang-3546 enrolled30 locationsNCT05998902
Recruiting
Phase 1

Phase I Split-Belt Treadmill Dosing for Subacute Stroke

Subacute strokeStrokeStroke, Subacute+1 more
University of Calgary72 enrolled1 locationNCT07469163
Recruiting
Not Applicable

Effects of tES Combined With CMDT Gait Training on Cognition, Cortical Activity, Spinal Motoneuron Excitability and Motor Performance in Stroke Individuals

Subacute strokeIschemic StrokeHemorrhagic Stroke+1 more
Mahidol University60 enrolled1 locationNCT07236216
Recruiting
Not Applicable

Body Composition and Acute Stroke

Acute Stroke
Centre Hospitalier Régional d'Orléans250 enrolled1 locationNCT06589297
Recruiting

mSOAR and Early Mortality in Acute Stroke

Acute Stroke
Sohag University60 enrolled1 locationNCT07355881
Recruiting
Not Applicable

Impact of Early, Personalized Nutritional Management on 1-month Mortality After Acute Stroke

Acute Stroke
University Hospital, Angers3,084 enrolled12 locationsNCT07065929
Recruiting
Phase 4

Early Administration of PCSK9 Inhibitors After Thrombectomy for Atherosclerotic Acute Ischemic Stroke: A Randomized Controlled Trial

Acute Stroke
The Affiliated Hospital of Xuzhou Medical University60 enrolled1 locationNCT07295366
Recruiting
Not Applicable

Using AI Systems to Optimize the Clinical Outcome of Stroke Patients

Acute Ischemic StrokeAcute StrokeAcute Stroke Intervention
Chinese University of Hong Kong400 enrolled1 locationNCT06828679
Recruiting
Not Applicable

SEACOAST 1- SEdAtion With COllAteral Support in Endovascular Therapy for Acute Ischemic Stroke

Acute Stroke
University of California, Los Angeles90 enrolled1 locationNCT03737786
Recruiting
Phase 4

Evaluation Study of Early Administration of Evolocumab After Thrombolysis in Patients With Atherosclerotic Acute Ischemic Stroke

Acute Stroke
The Affiliated Hospital of Xuzhou Medical University132 enrolled1 locationNCT07301372
Recruiting
Not Applicable

Isolated Versus Synergetic Muscle Facilitation on Upper Limb Functional Performance in Acute Stroke

Acute Stroke
Cairo University40 enrolled1 locationNCT07273201
Recruiting
Not Applicable

Ischemic Conditioning During Air tRansport Save penUmbral Tissue

Acute Stroke
Enrique Leira10 enrolled1 locationNCT03481205