RecruitingNot ApplicableNCT05698589

COMpassion for Psychiatric Disorders And Self-Stigma

Compassion Focused Therapy (CFT) for the Reduction of the Internalized Stigma of Mental Disorders: a Multi-center, Prospective, Randomized, Controlled Study


Sponsor

University Hospital, Strasbourg, France

Enrollment

336 participants

Start Date

Apr 3, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

People with mental disorders face frequent stigmatizing attitudes and behaviors from others . In response to this, they tend to isolate themselves, with the risk of impeding care and the process of recovery and integration into society . Stigmatization can also be assimilated by patients themselves - i.e. self-stigma. Self-stigma is involved in diminished coping skills that lead to social avoidance and difficulties in adhering to care . Reducing self-stigma and its emotional corollary, shame, is thus crucial to attenuate the disability associated with mental illness. Shame is inherent to self-stigma and leads to difficulties in adhering to care as well as greater severity of clinical presentations . Compassion Focused Therapy (CFT) is a third wave cognitive behavioral therapy that targets shame reduction and hostile self-to-self relationship and allows for symptom improvement while increasing self-compassion, a major resilience factor . Although shame is a prominent part of the concept of self-stigma, the efficacy of CFT has never been evaluated in individuals with high levels of self-stigma. In this study, the investigators will evaluate the efficacy and acceptability of a group based CFT program on decreasing self-stigma, compared to treatment as usual (TAU) and a psychoeducation program whose efficacy has been assessed in a previous trial.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Patient ≥18 years of age
  • Patient informed of the results of the preliminary medical examination
  • Patient affiliated to a social health insurance plan (beneficiary or beneficiary's family)
  • Patient with one or several diagnoses of chronic psychiatric disorder (schizophrenia, schizoaffective disorder, bipolar disorder, recurrent major depression, borderline personality disorder) or a neurodevelopmental disorder (autism spectrum disorder) treated as an outpatient or in a day hospital
  • CGI-Severity score\<6 assessed by the psychiatrist (Berk et al., 2008) ISMI score indicating moderate to high self-stigma (\>2.5; Lysaker et al., 2007)

Exclusion Criteria6

  • Patient in an exclusion period determined by a previous or ongoing study
  • Patient participating in an interventional study involving psychotherapy or an experimental drug
  • Patient in acute episode of their disorder according to the CGI Severity score
  • Patient in a medical emergency or immediate life-threatening situation
  • Patients with an intellectual disability (IQ\<70) estimated via the fNART (Mackinnon \& Mulligan, 2005)
  • \. Legal issues: care under constraint or patient deprived of freedom because of a judicial measure 13. Patient who does not speak and read French sufficiently

Interventions

BEHAVIORALCompassion Focused Therapy

CFT is an experiential therapy. As such, in addition to psychoeducation components (e.g.: compassion from an evolutionary and neuroscientific perspective, the tricky brain problem, emotion regulation systems) and explicit learning of emotion regulation skills (in particular, shame), experiential exercises are provided in-sessions (e.g. : chair work, role plays, guided mental imagery, …) and between sessions practices will be provided with video guides, made available for the participants online (e.g. : soothing rhythm breathing, safe place imagery, compassionate self-imagery, …). The overall aim of the CFT program is to help participants shift from a hostile and critical self-to-self relationship to a more compassionate relationship to self.

BEHAVIORALEnding Self Stigma

Psychoeducation sessions cover topics such as the path from public stigma to self-stigma and modifying self-stigmatizing thoughts. Participants will be encouraged to do home practices (e.g. writing about the pros and cons of self-stigmatizing thoughts) between sessions. The overall aim of the ESS program is to help participants address self-stigma with concrete tools to increase their self-esteem and achieve their goals


Locations(7)

Pôle de Psychiatrie Adulte, Hôpital Charles Perrens

Bordeaux, France

Ch Le Vinatier

Bron, France

CHU de Clermont-Ferrand, Hôpital Gabriel Montpied, Service de Psychiatrie B

Clermont-Ferrand, France

Pôle Hospitalo-Universitaire de Psychiatrie d'adultes et d'addictologie du Grand Nancy, Centre Psychothérapique de Nancy

Laxou, France

CHU de Montpellier, Psychiatrie d'adultes, Hôpital la Colombière

Montpellier, France

Etablissement Public de Santé Mentale (EPSM) de la Marne, Site Pierre-Briquet, Unité de réhabilitation psychosociale

Reims, France

Service de Psychiatrie, Hôpital Civil, Hôpitaux Universitaires de Strasbourg

Strasbourg, France

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NCT05698589


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