RecruitingNot ApplicableNCT05700279

Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset


Sponsor

Rush University Medical Center

Enrollment

345 participants

Start Date

Sep 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Although most people recover from acute pain (such as pain caused by injury, surgery, repetitive motion, or unknown causes), many people do not fully recover and will experience chronic pain. Untreated posttraumatic stress disorder (PTSD) appears to be a key risk factor for the transition from acute pain to chronic pain. However, few published studies have addressed the issue of preventing the transition from acute to chronic pain via PTSD reduction. This project will aim to test whether trauma-related PTSD symptoms can be reduced using either Stellate Ganglion Block (SGB) treatment or Cognitive Processing Therapy (CPT), and whether reducing PTSD symptoms can prevent the transition from non-injury based acute pain to chronic pain.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether treating PTSD symptoms early — at the same time as treating acute (new) pain in the emergency department — can prevent pain from becoming chronic (long-lasting). It's based on the idea that PTSD and chronic pain are closely linked. **You may be eligible if...** - You are 18–70 years old - You came to the Rush emergency department with a new, acute pain complaint - You have self-reported symptoms consistent with PTSD - You can read and write English well enough to complete questionnaires - People with well-controlled diabetes, HIV, or a stable psychiatric history may also be eligible **You may NOT be eligible if...** - You have a catastrophic or life-threatening injury requiring immediate intensive care - You have active, uncontrolled psychosis - Your neuropathic pain from a chronic condition is the reason for your ER visit Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDUREStellate Ganglion Block

Stellate Ganglion Block (SGB) procedure involves an injection of a local anesthetic (0.5% ropivacaine) around the stellate ganglion (a bundle of nerves located at the base of the neck) to block the transmission of pain signals. The SGB injection is administered by an anesthesiologist.

BEHAVIORALCognitive Processing Therapy

Cognitive Processing Therapy (CPT) is a form of trauma-based talk therapy that will be conducted by clinical therapists. CPT can help people identify and challenge unhelpful trauma-related beliefs about themselves, others, and the world.


Locations(1)

Rush University Medical Center

Chicago, Illinois, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05700279


Related Trials