RecruitingNCT05709769

Radiomics-based Malnutrition for Cervical Cancer.

Development and Validation of a CT-Based Radiomics Nomogram for the Prediction of Postoperative Malnutrition in Stage IB1-IIA2 Cervical Cancer (Nutrition Helper-1).

Sponsor

Zhejiang Provincial People's Hospital

Enrollment

150 participants

Start Date

Jan 31, 2023

Study Type

OBSERVATIONAL

Conditions

Cervical Cancer Malnutrition

Summary

Loss of skeletal muscle, is one of the most prevalent symptoms of malnutrition, and has been frequently reported as a negative factor in cancer patients at any disease stage. In this study, we are planning to firstly analyze the radiomics features of psoas extracted at the level of the third lumbar vertebra (L3) and then, develop a CT-based radiomics nomogram prediction model for predicting malnutrition based on their Patient-Generated Subjective Global Assessment (PG-SGA) scores in patients with International Federation of Gynecology and Obstetrics (FIGO, 2014 version) stage IB1-IIA2 cervical cancer (CC) who received postoperative radiotherapy/chemoradiotherapy (RT/CRT).

Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is using advanced imaging analysis (called radiomics) to predict which patients with early-stage cervical cancer are at risk of malnutrition before and during radiation or chemotherapy after surgery, so that nutrition support can be provided earlier. **You may be eligible if...** - You have been diagnosed with cervical cancer (stage IB1–IIA2) and had surgery to remove the uterus and lymph nodes - You are scheduled to receive radiation or chemoradiation after surgery - Your blood counts and organ function are within acceptable ranges - You are not allergic to platinum-based chemotherapy drugs - You are willing to follow the study's nutrition plan **You may NOT be eligible if...** - Your CT scan images are poor quality - You had chemotherapy or radiation before your surgery - You are participating in another clinical trial - You are pregnant or breastfeeding - You have uncontrolled infections, heart conditions, or other serious health conditions Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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