RecruitingPhase 4NCT05714007

The Effects of Ferric Derisomaltose on Postoperative Anemia in Spinal Deformity Surgery

The Effects of Ferric Derisomaltose on Postoperative Anemia in Patients Undergoing Spinal Deformity Surgery: A Prospective Randomized Controlled Study


Sponsor

Peking Union Medical College Hospital

Enrollment

120 participants

Start Date

Aug 31, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The prognosis of patients undergoing spinal deformity surgery is often compromised by perioperative anemia due to iron deficiency. The aim of this randomized, controlled trial was to evaluate whether postoperative ferric derisomaltose intravenous injection may improve anemia and prognosis in patients undergoing spinal deformity surgery comparing with oral iron. Participants will be randomly assigned to the treatment group (intravenous ferric derisomaltose) and the control group (oral iron). Changes in hemoglobin concentration, percentage of anemia correction, changes in iron indicators, patient quality of life, and incidence of adverse events will be analyzed to evaluate the efficacy and safety of iron isomaltoside infusion.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Ferric derisomaltose and a drug called Ferrous succinate for people with adult, perioperative anemia, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGFerric derisomaltose

Single intravenous dose ferric derisomaltose

DRUGFerrous succinate

Daily oral dose of 100 mg iron (ferrous succinate) tid postoperatively


Locations(1)

Peking Union Medical College Hospital

Beijing, Beijing Municipality, China

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NCT05714007


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