Spinal Deformity Clinical Trials

20 recruitingLast updated: May 22, 2026

There are 20 actively recruiting spinal deformity clinical trials across 12 countries. Studies span Not Applicable, Phase 3, Phase 4, Phase 2. Top locations include New York, New York, United States, San Francisco, California, United States, Durham, North Carolina, United States. Updated daily from ClinicalTrials.gov.


Spinal Deformity Trials at a Glance

20 actively recruiting trials for spinal deformity are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in New York, San Francisco, and Durham. Lead sponsors running spinal deformity studies include International Spine Study Group Foundation, Hospital for Special Surgery, New York, and The University of Hong Kong.

Browse spinal deformity trials by phase

Treatments under study

About Spinal Deformity Clinical Trials

Looking for clinical trials for Spinal Deformity? There are currently 15 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Spinal Deformity trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Spinal Deformity clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Not Applicable

The Ailliance Post-Market Clinical Study

Spinal DeformitySpinal Degenerative DisorderSpinal Fusion Failure+2 more
Medtronic Spinal and Biologics1,000 enrolled26 locationsNCT05856370
Recruiting
Phase 2Phase 3

Tranexamic Acid to Reduce Blood Loss in Spine Surgery

Spinal DeformitySpinal Injuries
Columbia University252 enrolled4 locationsNCT02314988
Recruiting

AI-Powered Scoliosis Auto-Analysis System Multicenter Development and Validations

Spinal Deformity
The University of Hong Kong2,500 enrolled1 locationNCT05146193
Recruiting
Phase 3

Tranexamic Acid in Adult Spinal Deformity Surgery

Blood Loss, SurgicalSpinal DeformityDegenerative Lumbar Spinal Stenosis
Hospital for Special Surgery, New York100 enrolled1 locationNCT03553186
Recruiting

Clariance ErYs Registry

Spinal TumorSpinal DeformitySpine Degeneration+2 more
Clariance760 enrolled1 locationNCT05170815
Recruiting
Not Applicable

Multimodal Bio-mechanical Analysis of Adult Spinal Deformity With Sagittal Plane Misalignment

Spinal Deformity
Universitaire Ziekenhuizen KU Leuven265 enrolled1 locationNCT04812730
Recruiting
Not Applicable

Balance Assessment Scale and Strength Measurement Protocol to Measure Functionality in Adults With Spinal Deformity

Spinal Deformity
Universitaire Ziekenhuizen KU Leuven30 enrolled1 locationNCT04642456
Recruiting

Prospective Evaluation of Complex Adult Spinal Deformity (CAD) Treated With Minimally Invasive Surgery

ScoliosisSagittal ImbalanceAdult Spinal Deformity+1 more
International Spine Study Group Foundation500 enrolled12 locationsNCT04885244
Recruiting

Prospective, Multicenter, Case-Control Analysis of the VersaTie Posterior Fixation System to Prevent Proximal Junctional Failure in Long Posterior Spinal Fusion Constructs for Adult Patients

ScoliosisAdult Spinal DeformityKyphosis
International Spine Study Group Foundation225 enrolled9 locationsNCT04888104
Recruiting

Complex Adult Deformity Surgery (CADS)

ScoliosisSagittal ImbalanceAdult Spinal Deformity+1 more
International Spine Study Group Foundation1,500 enrolled18 locationsNCT04194138
Recruiting
Phase 4

Post-Operative Thoracolumosacral Orthosis for PJK

Proximal Junctional KyphosisAdult Spinal Deformity SurgeryThoracolumbosacral Orthosis
Hospital for Special Surgery, New York84 enrolled6 locationsNCT06491030
Recruiting
Not Applicable

Feasibility of Wireless Continuous Vital Sign Monitoring and Impact on Patients Undergoing Adult Spinal Surgery in a General Ward

Remote MonitoringFeasibility StudiesAdult Spinal Deformity+4 more
Rigshospitalet, Denmark150 enrolled1 locationNCT07105189
Recruiting
Phase 4

The Effects of Ferric Derisomaltose on Postoperative Anemia in Spinal Deformity Surgery

SurgeryAdultSpinal Deformity+1 more
Peking Union Medical College Hospital120 enrolled1 locationNCT05714007
Recruiting
Not Applicable

Evaluating the Efficacy and Safety of Intra-wound Vancomycin Powder in High Risk Patients

Surgical Site InfectionTraumaSpinal Tumor+1 more
The University of Hong Kong76 enrolled1 locationNCT03839914
Recruiting
Not Applicable

Clinical Evaluation and Cost-effectiveness Analysis of 3D Digital Surgery in Traumatology

Vertebral Fracturehip osteoarthritisHip Arthritis+9 more
Corporacion Parc Tauli180 enrolled1 locationNCT06603831
Recruiting
Not Applicable

Efficacy of ARISTA-AH for Restoring Hemostasis Following Posterior Long-segment Spinal Fusion.

HemostasisSpinal FusionHemostatics+1 more
Polyclinique Bordeaux Nord Aquitaine100 enrolled1 locationNCT05323448
Recruiting

Intraoperative Monitoring for the Lateral Lumbar Interbody Fusion Procedure

Intervertebral disc degenerationSpondylolisthesisSpinal Instability+2 more
Alphatec Spine, Inc.400 enrolled1 locationNCT05648474
Recruiting
Not Applicable

Pedicle Screw Malposition in Spine Arthrodesis Surgeries With O-ARM-guided Navigation

Spinal FusionSpinal DeformitySpine Injury
Federal University of Piaui124 enrolled1 locationNCT06020417
Recruiting

Adherence to Physiotherapy Scoliosis Specific Exercises in Adolescents With Spine Deformity: Development of a New Questionnaire

Adherence, TreatmentSpinal Deformity
Istituto Scientifico Italiano Colonna Vertebrale600 enrolled1 locationNCT05433545
Recruiting

Research of Factors Determining the Improvement of Quality of Life at One Year of Adult Patients Treated for Spinal Deformity (COFTASD)

Spinal Deformity
Elsan866 enrolled1 locationNCT05108948