RecruitingNot ApplicableNCT05732779

Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients

Mobile Video Directly Observed Therapy (DOT) for Immunosuppression Medication Adherence in Adolescent Heart Transplant Recipients: Enhancing Technological Innovation and Strengthening the Role of Small Businesses in Meeting Needs of Adolescent Organ Transplant


Sponsor

University of Florida

Enrollment

100 participants

Start Date

Oct 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

We will conduct a two-group randomized controlled trial to examine the eMocha DOT intervention with pediatric HT recipients.In this population, medication nonadherence remains a primary cause of late acute rejection (LAR) episodes, increased number of hospitalizations, graft failure, and patient mortality. Herein, we propose an innovative approach to promote medication adherence and improve patient and graft outcomes.


Eligibility

Min Age: 10 YearsMax Age: 21 Years

Inclusion Criteria6

  • Eligible participants are 10-21 years of age
  • Have received a heart transplant and are followed participating pediatric heart transplant centers
  • English-speaking or Spanish-speaking
  • Own a smart-phone or have access to the mobile app through other devices
  • Are willing to receive information through it
  • Have a MLVI score of greater than 2.0 over the last year

Exclusion Criteria1

  • Those with cognitive impairments will not be eligible for enrollment due to inability to provide informed assent

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Interventions

OTHERDOT intervention

A mobile health application developed by eMocha Health Inc. facilitates asynchronous mobile video directly observed therapy (DOT) intervention, empowering users to track dose-by-dose medication adherence


Locations(4)

University of Miami, Miller School of Medicine

Coral Gables, Florida, United States

University of Florida

Gainesville, Florida, United States

Joe DiMaggio Children's Hospital

Hollywood, Florida, United States

FSU College of Medicine

Tallahassee, Florida, United States

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NCT05732779


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