RecruitingNCT05734430
Genetics of Appendix Cancer Study
Genetics of Appendix Cancer: The GAP Study
Sponsor
Andreana Holowatyj, PhD, MSCI
Enrollment
700 participants
Start Date
Nov 11, 2022
Study Type
OBSERVATIONAL
Conditions
Appendiceal CancerAppendix CancerAppendiceal AdenocarcinomaAppendiceal NeoplasmsAppendiceal Mucinous NeoplasmAppendiceal Carcinoid TumorAppendiceal Neoplasm Malignant SecondaryAppendix AdenocarcinomaAppendix Mucinous NeoplasmAppendix TumorAppendix Cancer MetastaticAppendix NETLow-Grade Appendix Mucinous NeoplasmHigh Grade Appendix Mucinous NeoplasmHigh Grade Appendix Mucinous Adenocarcinoma
Summary
The GAP Study is a prospective cohort study designed to comprehensively investigate genetic variations that may contribute to cancer development among individuals diagnosed with appendix/appendiceal cancer who are ages 18+ years.
Eligibility
Min Age: 18 Years
Inclusion Criteria11
- GAP Social
- Known diagnosis of appendix cancer in the United States
- Mentally and physically able to consent and participate in the study
- GAP Vanderbilt
- Known diagnosis of appendix cancer
- Diagnosed by and/or consulting with a physician/clinical provider participating in the GAP Study
- Mentally and physically able to consent and participate in the study
- GAP Parent
- Biological parents (mother and/or father) of individuals actively participating in the GAP Study
- Residing in the United States
- Mentally and physically able to consent and participate in the study
Exclusion Criteria4
- Women pregnant at the time of consent
- Prisoners
- Unable to provide informed consent
- Unable to read, write, or complete questionnaires in English
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Interventions
GENETICGenetic profiling
Whole exome sequencing
OTHERRetrospective tissue procurement
Collection of archived fixed-formalin, paraffin-embedded (FFPE) primary appendix tumor tissues that were previously removed
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05734430
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