Appendiceal Cancer Clinical Trials

8 recruitingLast updated: June 17, 2026

There are 8 actively recruiting appendiceal cancer clinical trials across 3 countries. Studies span Not Applicable, Phase 1, Phase 4. Top locations include Bethesda, Maryland, United States, Duarte, California, United States, Los Angeles, California, United States. Updated daily from ClinicalTrials.gov.


Appendiceal Cancer Trials at a Glance

8 actively recruiting trials for appendiceal cancer are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Bethesda, Duarte, and Los Angeles. Lead sponsors running appendiceal cancer studies include Azienda Ospedaliera di Padova, Cedars-Sinai Medical Center, and Andreana Holowatyj, PhD, MSCI.

Browse appendiceal cancer trials by phase

Treatments under study

About Appendiceal Cancer Clinical Trials

Looking for clinical trials for Appendiceal Cancer? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Appendiceal Cancer trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Appendiceal Cancer clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

Molecular Profiling for Risk Stratification in Appendiceal Cancer

Appendiceal CancerAppendiceal Adenocarcinoma
City of Hope Medical Center400 enrolled1 locationNCT07587268
Recruiting
Phase 1

Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies

Colorectal, CancerOvarian CancerPeritoneal Carcinomatosis+4 more
National Cancer Institute (NCI)60 enrolled1 locationNCT04847063
Recruiting
Not Applicable

A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis

Colorectal AdenocarcinomaPeritoneal MetastasesAppendiceal Cancer
Yale University20 enrolled1 locationNCT07291180
Recruiting
Phase 4

Intraoperative Imaging of Gastrointestinal Malignancies Using Pafolacianine (CYTALUX™)

Esophageal CancerGastric CancerGastrointestinal Cancer+1 more
Cedars-Sinai Medical Center15 enrolled1 locationNCT07124351
Recruiting

An International Study on Pediatric Patients With Rare Tumors.

MesotheliomaThyroid CarcinomaPleuropulmonary Blastoma+11 more
Azienda Ospedaliera di Padova6,250 enrolled1 locationNCT07072143
Recruiting

Genetics of Appendix Cancer Study

Appendiceal CancerAppendix CancerAppendiceal Adenocarcinoma+12 more
Andreana Holowatyj, PhD, MSCI700 enrolled1 locationNCT05734430
Recruiting
Not Applicable

Locally ablatIVe thErapy for oLigo-progressive gastrOintestiNal maliGnancies (LIVELONG)

Colorectal, CancerEsophageal CancerGastric Cancer+8 more
University of California, Davis300 enrolled1 locationNCT06101277
Recruiting

Molecular Characterisation of Appendiceal Cancer

Appendiceal Cancer
The Christie NHS Foundation Trust100 enrolled1 locationNCT05364788