RecruitingNCT05750212

Musculoskeletal and Pelvic Floor Health in Female Chronic Overlapping Pelvic Pain Conditions

Musculoskeletal and Pelvic Floor Health in Female Chronic Overlapping Pelvic Pain Conditions (The MSK-PELVIC Study)


Sponsor

Loyola University

Enrollment

208 participants

Start Date

Jan 24, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

The purpose of this study is to learn about nerve function and pelvic muscle function. To do this we will compare the pelvic nerve and muscle function of women with chronic pelvic pain to those who do not have chronic pelvic pain. Understanding the pain may lead to better treatments in the future.


Eligibility

Sex: FEMALEMin Age: 21 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is examining the relationship between musculoskeletal problems (such as muscle tension and joint dysfunction in the pelvis, hips, and spine) and pelvic floor dysfunction in women with chronic overlapping pelvic pain conditions. These conditions — including interstitial cystitis, irritable bowel syndrome, endometriosis, vulvodynia, pudendal neuralgia, fibromyalgia, and pelvic floor muscle pain — frequently occur together, yet are often treated in isolation by different specialists. This research aims to better characterize the full physical picture of these overlapping pain syndromes. To participate, you must be female, between 21 and 80 years old, have had symptoms of chronic pelvic pain for more than 6 months as defined by the American College of Obstetrics and Gynecology, have at least two of the seven specified overlapping conditions, and report an average pain score of at least 3 out of 10. You cannot participate if you have a current or past pelvic cancer, an active pelvic infection, are pregnant or recently gave birth (within 6 months), or have had abdominal or pelvic surgery within the past 3 years. Participants will undergo specialized physical assessments of the pelvic floor and musculoskeletal system. This research is important because chronic pelvic pain is highly prevalent and frequently misunderstood or inadequately treated — identifying common musculoskeletal patterns could open up new, more effective rehabilitative treatment pathways.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTTone

Tone is a binary measurement of the pelvic floor muscle on physical examination

DIAGNOSTIC_TESTTenderness

Tenderness is a binary measurement of the pelvic floor muscle on physical examination

DIAGNOSTIC_TESTContraction

Contraction is a binary measurement of the pelvic floor muscle on physical examination

DIAGNOSTIC_TESTRelaxation

Relaxation is a binary measurement of the pelvic floor muscle on physical examination

DIAGNOSTIC_TESTElectromyography

Electromyography is a measurement of the pelvic floor muscle in microvolts

DIAGNOSTIC_TESTTransperineal

Transperineal measurements (in millimeters) of the pelvic floor muscle using an ultrasound

DIAGNOSTIC_TESTPressure

Pressure measurements (in millimeters) of the pelvic floor muscle using an algometer


Locations(1)

Loyola Medical Center

Maywood, Illinois, United States

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NCT05750212


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