RecruitingNCT05759637

Type 2 Diabetes, Obesity and Cortisol Excess


Sponsor

Istituto Auxologico Italiano

Enrollment

3,200 participants

Start Date

May 6, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

The present observational cross-sectional study is aimed to assess: the hidden hypercortisolism (HidHyCo) prevalence in a sample of Type 2 diabetes (T2D) patients and the clinical characteristics more frequently associated with the HidHyCo presence and the HidHyCo prevalence in an adequate sample of obese patients without T2D and the clinical characteristics more frequently associated with the HidHyCo presence.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether people with both type 2 diabetes and obesity might have hidden excess cortisol (a stress hormone) that is contributing to high blood pressure. It also looks at a separate group of people with obesity who do not have diabetes. **You may be eligible if...** - You have type 2 diabetes and obesity, OR - You have obesity without type 2 diabetes (for the comparison group) **You may NOT be eligible if...** - You are pregnant or breastfeeding - You have sleep apnea - You have a known adrenal tumor or another confirmed cause of high blood pressure - You already show signs of excessive cortisol (Cushing's syndrome symptoms) - You have severe autoimmune, blood, or kidney disease (kidney filter rate under 60) - You use medications that affect the cortisol system - You have type 2 diabetes (this is an exclusion for the comparison group only) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIAGNOSTIC_TEST1mg DST

measurement of cortisol levels after 1 mg of dexamethasone (DST) at 11 pm


Locations(5)

Istituto Auxologico Italiano

Milan, Italy

Niguarda Hospital

Milan, Italy

Campus Bio-Medico University

Roma, Italy

University of Siena

Siena, Italy

Azienda Ospedaliero Universitaria, Santa Maria della Misericordia di Udine

Udine, Italy

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05759637


Related Trials