TAD After Chemotherapy in Locally Advanced Breast Cancer

This trial is studying a surgical technique called TAD (targeted axillary dissection) in people with locally advanced breast cancer who have received pre-surgery chemotherapy. TAD aims to remove fewer lymph nodes than standard surgery while still accurately checking whether the cancer has responded to chemotherapy, reducing side effects like arm swelling (lymphedema). **You may be eligible if...** - Your breast cancer has spread to underarm lymph nodes (confirmed by biopsy) - You have at least 4 suspicious underarm lymph nodes, or a large tumor requiring underarm lymph node removal - You are receiving pre-surgery (neoadjuvant) chemotherapy **You may NOT be eligible if...** - Your cancer has spread very extensively to lymph nodes (cN3 stage) - Your breast cancer is the "luminal A" molecular subtype - You are receiving only hormone therapy (not chemotherapy) before surgery - You have cancer that has come back locally or spread to distant organs (metastatic) Talk to your doctor to see if this trial is right for you.