Sentinel Lymph Node Clinical Trials

27 recruiting

Sentinel Lymph Node Trials at a Glance

37 actively recruiting trials for sentinel lymph node are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 17 trials, with the heaviest enrollment activity in Kunming, Copenhagen, and Barcelona. Lead sponsors running sentinel lymph node studies include Yunnan Cancer Hospital, Hospital Universitari de Bellvitge, and European Institute of Oncology.

Browse sentinel lymph node trials by phase

Treatments under study

About Sentinel Lymph Node Clinical Trials

Looking for clinical trials for Sentinel Lymph Node? There are currently 27 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sentinel Lymph Node trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sentinel Lymph Node clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 37 trials

Recruiting
Not Applicable

ALND vs ART in Positive Sentinel Node After Neoadjuvant Therapy in Breast Cancer

Breast CancerRadiotherapy Side EffectSentinel Lymph Node+2 more
Hospital Universitari de Bellvitge820 enrolled60 locationsNCT04889924
Recruiting

Patent Blue SLN in Early Ovarian Cancer Prospective Study (FIGO I-II) Evaluating Patent Blue SLN Mapping. Injection Into IP/UO Ligaments in Situ. Goals: Assess Feasibility and Accuracy vs Standard Lymphadenectomy to Minimize Surgical Morbidity

Sentinel Lymph Node Biopsy (SLNB)Early Stage Ovarian Tumors
Faculty of Medicine of Tunis30 enrolled1 locationNCT07508306
Recruiting
Not Applicable

Axillary Management in Breast Cancer Patients With Needle Biopsy Proven Nodal Metastases After Neoadjuvant Chemotherapy

Breast CancerSentinel Lymph NodeNeoplasm, Breast
University Hospitals of Derby and Burton NHS Foundation Trust1,900 enrolled98 locationsNCT04109079
Recruiting

Audit of Targeted Sentinel Node Biopsy (TSNB) in Patients With Limited Nodal Disease Undergoing Primary Surgery

Breast CancerSentinel Lymph Node Biopsy (SLNB)Axillary Lymph Nodes Dissection+1 more
University Hospitals of Derby and Burton NHS Foundation Trust200 enrolled12 locationsNCT07085442
Recruiting

Upfront Targeted Axillary Dissection for Luminal Breast Cancer With Limited Axillary Involvement

Sentinel Lymph Node Biopsy (SLNB)ALNDTargeted Axillary Dissection (TAD)
European Institute of Oncology150 enrolled14 locationsNCT07278726
Recruiting
Phase 3

Sentinel Node Biopsy in Endometrial Cancer

SurgerySentinel Lymph NodeEndometrial Cancer Stage I
Queensland Centre for Gynaecological Cancer760 enrolled19 locationsNCT04073706
Recruiting
Phase 3

No Axillary Surgical Treatment in Clinically Lymph Node Negative Patients on Ultrasonography After Neoadjuvant Chemotherapy

Breast CancerNeoadjuvant TherapySentinel Lymph Node Biopsy
Seoul National University Hospital464 enrolled1 locationNCT06704945
Recruiting
Not Applicable

Finding Sentinel Lymph Nodes During Mastectomy Using Indocyanine Green (INIGMA Study)

Breast CancerMastectomySentinel Lymph Node Biopsy (SLNB)+7 more
Isabelle Henskens90 enrolled2 locationsNCT07362485
Recruiting

Does Ultrasound Guidance Axillary Incision Improve Sentinel Lymph Node Detection in Breast Cancer?

Breast CarcinomaSentinel Lymph Node Biopsy
Antalya Training and Research Hospital40 enrolled1 locationNCT07338721
Recruiting
Not Applicable

Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer

Breast CancerSentinel Lymph Node Biopsy (SLNB)Sentinel Lymph Node Detection+6 more
Isabelle Henskens1,760 enrolled7 locationsNCT07146295
Recruiting
Not Applicable

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in IBC

Sentinel Lymph Node Biopsy (SLNB)Invasive Breast CarcinomaNeoadjuvant Chemotherapy
European Institute of Oncology75 enrolled1 locationNCT07080944
Recruiting
Not Applicable

Refining Local-Regional Therapy for IBC

Breast CancerSentinel Lymph NodeInflammatory Breast Cancer
Dana-Farber Cancer Institute50 enrolled1 locationNCT04636710
Recruiting
Not Applicable

Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma

Sentinel Lymph NodeIndocyanine Green (ICG)Colon Cancer+9 more
Meander Medical Center341 enrolled1 locationNCT06652672
Recruiting
Phase 1Phase 2

Bronchial NIR Image-guided Resection

Sentinel Lymph Node
Massachusetts General Hospital100 enrolled1 locationNCT03097575
Recruiting

TAD After Chemotherapy in Locally Advanced Breast Cancer

Breast CancerSentinel Lymph NodeLocally Advanced
Hospital Universitari de Bellvitge162 enrolled2 locationsNCT05763641
Recruiting

Rapid Assessment of Sentinel Lymph Node Metastasis Status Using a Pan-CK-targeting NIR-II Fluorescent Probe in Breast Cancer

Breast Cancer MetastaticSentinel Lymph Node Biopsy (SLNB)Sentinel Lymph Node+1 more
Yunnan Cancer Hospital60 enrolled1 locationNCT07154563
Recruiting
Not Applicable

Sentinel Node Biopsy Versus Limited Elective Neck Dissection in Early Cancers of Oral Cavity NoDe Negative

Sentinel Lymph Node Biopsy (SLNB)Sentinel Lymph NodeSentinel Lymph Node Biopsy+4 more
Tata Memorial Hospital508 enrolled3 locationsNCT05774483
Recruiting
Not Applicable

Comparison of Two-Position and Four-Position Cervical Injection Techniques for Sentinel Lymph Node Mapping in Endometrial Cancer Using Methylene Blue

Sentinel Lymph NodeMetastasisEndometrial Neoplasms+1 more
Dokuz Eylul University100 enrolled2 locationsNCT07040657
Recruiting
Not Applicable

Application of EndoScell Intraoperative Cellular Probing Technology for Early-Stage Breast Cancer

Breast CancerSentinel Lymph NodeFrozen Section+1 more
Fudan University709 enrolled1 locationNCT06911528
Recruiting
Not Applicable

Peritumoral Microbubbles and CEUS for SLN Detection and Biopsy in HNSCC

Sentinel Lymph NodeHead and Neck Squamous Cell Carcinoma
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University70 enrolled1 locationNCT05437380