Role of Liquid Biopsies in HPV-associated Cancer Treatment Monitoring
Liquid Biopsies - a Possible Tool for Treatment Monitoring and Early Recurrence Detection in HPV-associated Diseases
The Institute of Molecular and Translational Medicine, Czech Republic
480 participants
Jun 1, 2022
OBSERVATIONAL
Conditions
Summary
This trial will evaluate the possible benefits and the performance of liquid biopsies in HPV-associated cancer treatment monitoring. This study aims to find a combination of an adequately sensitive and specific sampling method and biomarkers for early risk stratification of disease recurrence.
Eligibility
Inclusion Criteria1
- Women diagnosed with CC/HSIL. Men and women diagnosed with OPC. Patients must agree with study enrollment and must sign study informed consent.
Interventions
Patients will be asked to perform self-collection of gargle lavage samples. Oropharyngeal swabs, breath condensate, and blood samples will be taken by trained clinicians.
Patients will be asked to perform cervicovaginal self-sampling using Evalyn Brush. Blood samples will be taken by trained clinicians.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05774561