RecruitingNCT05778981

Endothelial Dysfunction and Non-cardiac Surgery

Endothelial Dysfunction During Non-cardiac Surgery and Major Clinical Events


Sponsor

University of Chile

Enrollment

200 participants

Start Date

Mar 25, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Endothelial dysfunction is a cardiovascular disease hallmark. After non-cardiac surgery, cardiovascular events correlate with surgical outcomes. Understanding the role of endothelial function in these events is crucial. This research aims to study endothelial function and its association with cardiovascular events.


Eligibility

Min Age: 45 Years

Inclusion Criteria2

  • Signed informed consent
  • Patients 45 years or older

Exclusion Criteria5

  • Refuse to participate in the study
  • Myocardial injury or acute myocardial infarction less than two weeks ago
  • Patients who expect less than 2 days of hospitalization
  • Patients in whom the troponin elevation is attributed to a secondary cause (for example, sepsis, pulmonary thromboembolism, electrical cardioversion, etc.)
  • Use of chemotherapy less than 2 weeks ago

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Interventions

DIAGNOSTIC_TESTFMD - Troponin measurement

Echographic FMD evaluation. Pre and post-operative troponin measurements.


Locations(1)

Hospital Clínico de la Universidad de Chile

Independencia, Santiago Metropolitan, Chile

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NCT05778981


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