RecruitingNot ApplicableNCT05782829

Perioperative Stress Management in Outpatient Surgery With L-tyrosine Supplementation (SPOT)

Perioperative Stress Management in Outpatient Surgery With L-tyrosine Supplementation


Sponsor

Centre Hospitalier Universitaire de Nice

Enrollment

150 participants

Start Date

Nov 14, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Patient undergoing surgery is exposed to many stressors: diachronic (gesture anticipation), synchronic (intraoperative aggression) and historical (subject's personality). Reducing the level of stress experienced is a factor for improving the quality of the surgical gesture and the simplicity of the follow-up. The previous methods used were intended to reduce the body's reactivity to aggressions through anaesthesia consultation and L-Tyrosine supplementation. Currently with the progression of outpatient surgery and the need for early rehabilitation, L-Tyrosine supplementation is suppressed to improve recovery. Some patients, however, have a high level of stress that may require anxiolysis when the ideal treatment does not exist (ineffective hydroxyzine, benzodiazepines having many side effects). The strategy of this work is to improve the body's ability to respond to stressors, by administering l-tyrosine with no impact on waking or returning home.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying L-tyrosine supplementation and Placebo supplementation for people with stress. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years to 75 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTL-tyrosine supplementation

L-Tyrosine supplementation before surgery for inguinal hernia under general anaesthesia

DIETARY_SUPPLEMENTPlacebo supplementation

Placebo supplementation before surgery for inguinal hernia under general anaesthesia


Locations(1)

CHPG

Monaco, Monaco

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NCT05782829


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