MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

This study is testing whether MDMA (commonly known as ecstasy) combined with cognitive behavioral therapy (CBT) can reduce symptoms of obsessive-compulsive disorder (OCD). MDMA is being studied as a tool to make therapy more effective by reducing fear and increasing openness during sessions. Participants receive MDMA in a supervised clinical setting alongside structured therapy. **You may be eligible if:** - You are at least 18 years old - You have a confirmed diagnosis of OCD with a moderate-to-severe symptom score (YBOCS ≥16) - You have not been on any psychiatric medications for at least 1 month prior to starting - You have tried and failed at least one standard first-line OCD treatment - You are willing to fast and follow the required safety guidelines before sessions **You may NOT be eligible if:** - You are currently taking psychotropic medications - You are unable or unwilling to stop medications temporarily for the study - You have medical or psychiatric conditions that prevent you from safely tolerating the study procedures Talk to your doctor to see if this trial is right for you.