RecruitingNCT05784038

Observational, Prospective, Cohort Study of Mpox Infection in Brazil (NETPOX)

Observational, Prospective, Cohort Study of Mpox Infection in Brazil - NETPOX Cohort


Sponsor

Hospital Israelita Albert Einstein

Enrollment

80 participants

Start Date

Jul 16, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The study is a prospective cohort that evaluates the clinical and immune-metabolic variables that may be linked to the risk and severity of the infection or even hospitalization or death in patients infected with the Mpox virus in Brazil. The expectation is to include at least 80 patients over six months, with a follow-up of 90 days from inclusion, through contact via decentralized visits.


Eligibility

Min Age: 18 Years

Inclusion Criteria2

  • Men and women aged ≥ 18 years with confirmed MPOX infection.
  • (laboratory-confirmed monkeypox infection is defined as determined by PCR, culture, or antigen test obtained from a sample collected from blood, oropharynx, anal or skin lesion within 4 days of randomization)

Exclusion Criteria2

  • Inability to provide informed consent;
  • Patient who, judging by the study team, does not have a condition for decentralized follow-up

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Interventions

DIAGNOSTIC_TESTViral genomic

Evaluation of mpox viral genomic

DIAGNOSTIC_TESTUntargeted Metabolomics

Evaluation of metabolomics of the total plasma, oropharynx, and skin samples.


Locations(3)

Hospital Universitário João de Barros Barreto

Belém, Pará, Brazil

Hospital Israelita Albert Einstein

São Paulo, São Paulo, Brazil

Hospital Naval Marcílio Dias

Rio de Janeiro, Brazil

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NCT05784038


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