Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI
Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI (-COMPLETE-NSTEMI-)
Leipzig Heart Science gGmbH
3,390 participants
Oct 27, 2023
INTERVENTIONAL
Conditions
Summary
Prospective, randomized, controlled, multicenter, open-label trial to study whether multivessel percutaneous coronary intervention (PCI) is superior over culprit-lesion only PCI in patients with non-ST-segment elevation myocardial infarction (NSTEMI) and multivessel coronary artery disease.
Eligibility
Inclusion Criteria4
- NSTEMI as suggested by high-sensitivity troponin algorithms
- Multivessel coronary artery disease
- Identifiable culprit lesion
- Informed consent
Exclusion Criteria10
- Age <18 years
- Cardiogenic shock
- Sustained ventricular tachycardia (VT) or ventricular fibrillation (VF)
- Contraindication for coronary revascularization
- Prior coronary artery bypass graft
- Indication for coronary artery bypass graft surgery
- Non-culprit lesion located in the left main coronary artery
- Co-morbidity with life expectancy less than 6 months
- Type 2 myocardial infarction
- Pregnancy and breast feeding period
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Interventions
Percutaneous coronary intervention of culprit-lesion
Complete percutaneous coronary intervention of all angiographically significant non-culprit lesions
Locations(58)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05786131