RecruitingNot ApplicableNCT05800132

Diagnostic Performance of Breast Cancer Screening Second Reading Process Assisted by AI

Évaluation de la Performance Diagnostique du dépistage du Cancer du Sein, Pour Une Seconde Lecture Des clichés de Mammographie assistée du Dispositif médical à Base d'Intelligence Artificielle MammoScreen

Sponsor

Therapixel

Enrollment

5,000 participants

Start Date

Jun 1, 2023

Study Type

INTERVENTIONAL

Conditions

Breast Cancer

Summary

The goal of this clinical trial is to compare, for the second reading of screening mammograms, the standard of care with an AI assisted scenario. The main questions it aims to answer are: * will the experimental pathway be non-inferior to the standard pathway? * will the experimental pathway be economically superior to the standard pathway? Participants will receive screening mammograms, as part of the breast cancer screening program. Researchers will compare the interpretation made by the second reader in the standard pathway with the AI assisted interpretation made by a different reader in the experimental pathway.

Eligibility

Sex: FEMALEMin Age: 50 YearsMax Age: 74 Years

Inclusion Criteria5

Affiliated to the French social security system
Whose mammograms meet the following characteristics: 4 (2 per breast, CC and MLO) meeting local regulatory standards and with correct DICOM metadata,
Whose mammograms have been determined to be normal or to have benign lesions by the radiologist who performed the first reading of the images (L1) in the framework of the organized breast cancer screening program
Having expressed her willingness to participate in the study, to undergo all the procedures and to make herself available for the expected duration of their participation,
Having completed and signed the informed consent form.

Exclusion Criteria7

Woman with breast implants,
With clinical symptoms of breast cancer,
With a history of breast surgery (breast reduction or surgery for benign lesion),
Pregnant or breastfeeding,
With medical conditions that may interfere with her ability to understand the requirements of the protocol or give informed consent,
Deprived of liberty by judicial or administrative order,
Participant whose mammogram images have at least one of the following defects: poor quality of the images, non-standard mammography (projection, magnification, compression), ML/LM/SIO/XCCL or XCCM view.