RecruitingNCT05800639

Frontal Alpha Asymmetry and Pediatric Emergence Delirium

Mediation Role of Perioperative Electroencephalogram Frontal Alpha Asymmetry to Pediatric Emergence Delirium


Sponsor

Gangnam Severance Hospital

Enrollment

80 participants

Start Date

Apr 6, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This study aimed to investigate whether the association between the preoperative anxiety level and emergence delirium involves EEG frontal alpha asymmetry in pediatric patients undergoing ophthalmic surgery under general anesthesia. The investigators hypothesized that EEG frontal alpha asymmetry contributes a significant portion of the preoperative anxiety - emergence delirium association in pediatric patients. Mediation analysis will be performed to estimate the relationships between preoperative anxiety of children (modified Yale Preoperative Anxiety Scale (mYPAS)), EEG frontal alpha asymmetry, and emergence delirium (Pediatric Assessment of Emergence Delirium (PAED) scale).


Eligibility

Min Age: 2 YearsMax Age: 8 Years

Inclusion Criteria3

  • Children aged 2-8 year
  • Children with an American Society of Anesthesiologists (ASA) physical status of I-II
  • Children who are scheduled to undergo elective ophthalmological requiring general anesthesia

Exclusion Criteria6

  • Emergency surgery
  • Patients with developmental delays
  • Patients with neurological or psychiatric diseases associated with symptoms of agitation, anxiety, attention deficit, sleep disturbances
  • Patients with autism
  • Patients with a recent history (within one month) of receiving general anesthesia
  • Patients with congenital or genetic diseases that may influence brain development

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Interventions

PROCEDUREOphthalmic surgery

Ophthalmic surgery will be performed as standard practice of our institution.

PROCEDUREGeneral anesthesia

General anesthesia will be performed as standard practice of our institution.


Locations(1)

Gangnam Severance Hospital

Seoul, South Korea

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NCT05800639


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