Total Intravenous Anesthesia (TIVA)/Sevoflurane Initiated Intravenous Anesthesia (SIIVA) in Pediatric Patients
A Prospective Observational Study Evaluating Extubation Criteria in Children Less 10 Years of Age and Younger Undergoing Intravenous Anesthesia
Wake Forest University Health Sciences
600 participants
Mar 28, 2023
OBSERVATIONAL
Conditions
Summary
Because Propofol is the primary "anesthetic agent," and inhalational agents remain in trace quantities at the end of the procedure Sevoflurane initiated intravenous anesthesia (SIIVA) or not present at all Total intravenous anesthesia (TIVA) it is likely that different criteria may be predictive of extubation success in these patients compared to inhalational anesthesia.
Eligibility
Inclusion Criteria5
- Pediatric patients \<10 years of age
- Undergoing elective or emergency surgery with planned airway instrumentation with an endotracheal tube (ETT)
- Patients having general anesthesia with a planned SIIVA or TIVA technique
- Patients with an end tidal agent concentration of Sevoflurane\<0.1% at the time of emergence and extubation
- following sevoflurane induction to place IV
Exclusion Criteria7
- History of home oxygen use or ventilator dependence
- Patients with cyanotic congenital heart disease
- Patients undergoing anesthesia for imaging procedures alone
- Patients intended to be managed with supraglottic airway
- Patients having an anesthesia time \< 30 minutes
- Monitored Anesthesia Care (not general anesthesia)
- Patients with contraindication to receiving Propofol (i.e. mitochondrial myopathy)
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Interventions
TIVA anesthetic -no inhalational gases for surgery
SIIVA - sevoflurane anesthetic gases for surgery
Locations(2)
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NCT05837936