RecruitingNCT06442930

EXtubation Related Complications - the EXTUBE Study (EXTUBE)

EXtubation Related Complications - an International Observational Study To Understand the Impact and BEst Practices in the Operating Room and Intensive Care Unit - the EXTUBE Study


Sponsor

University Health Network, Toronto

Enrollment

3,000 participants

Start Date

Apr 14, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

EXTUBE is an international, multicentre, prospective cohort study evaluating the incidence, risk factors, and outcomes of extubation-related complications and describing clinical practices related to extubation after general anesthesia or after critical illness in the operating room (OR), out of OR anesthesia location or intensive care unit (ICU).


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Adult patients (≥18 years old)
  • Undergoing extubation of an endotracheal tube (including index extubation and re-extubations) after general anesthesia in the OR, out of OR anesthesia location or ICU
  • Undergoing extubation during the specified enrollment window

Exclusion Criteria3

  • Patients will be excluded if the extubation is performed in the context of withdrawal of life support measures,
  • Patients will be excluded if the extubation is performed for tracheostomy decannulation
  • For each patient who is not included, reasons for exclusion will be reported.

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Locations(25)

Banner University Medical Centre

Tucson, Arizona, United States

University of Arkansas for Medical Sciences

Little Rock, Arkansas, United States

University of Florida

Gainesville, Florida, United States

Oregon Health & Science University

Portland, Oregon, United States

The University of Texas Health Science Center

Houston, Texas, United States

Royal North Shore Hospital

Sydney, New South Wales, Australia

The Northern Hospital

Melbourne, Victoria, Australia

Austin Hospital

Melbourne, Victoria, Australia

Eastern Health - Box Hill Hospital

Melbourne, Victoria, Australia

Eastern Health - Maroondah Hospital

Melbourne, Victoria, Australia

Eastern Health - Angliss Hospital

Melbourne, Victoria, Australia

Surrey Memorial Hospital

Surrey, British Columbia, Canada

The Moncton Hospital

Moncton, New Brunswick, Canada

Sunnybrook Hospital

North York, Ontario, Canada

Niagara Health - Marotta Family Hospital

Saint Catharines, Ontario, Canada

St. Michael's Hospital

Toronto, Ontario, Canada

Mount Sinai Hospital

Toronto, Ontario, Canada

University Health Network - Toronto General Hospital

Toronto, Ontario, Canada

University Health Network - Toronto Western Hospital

Toronto, Ontario, Canada

Cork University Hospital

Cork, Ireland

Mater Misericordiae University Hospital

Dublin, Ireland

Galway University Hospitals

Galway, Ireland

Tan Tock Seng Hospital

Singapore, Singapore

Royal United Hospitals Bath

Bath, United Kingdom

Freeman Hospital

Newcastle upon Tyne, United Kingdom

View Full Details on ClinicalTrials.gov

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NCT06442930


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