Coronary Microvascular Dysfunction Clinical Trials

16 recruiting

Coronary Microvascular Dysfunction Trials at a Glance

20 actively recruiting trials for coronary microvascular dysfunction are listed on ClinicalTrialsFinder across 6 cities in 17 countries. The largest study group is Not Applicable with 5 trials, with the heaviest enrollment activity in London, Boston, and Beijing. Lead sponsors running coronary microvascular dysfunction studies include Brigham and Women's Hospital, Cedars-Sinai Medical Center, and Azienda Ospedaliera Universitaria Integrata Verona.

Browse coronary microvascular dysfunction trials by phase

Treatments under study

About Coronary Microvascular Dysfunction Clinical Trials

Looking for clinical trials for Coronary Microvascular Dysfunction? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Coronary Microvascular Dysfunction trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Coronary Microvascular Dysfunction clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 20 trials

Recruiting
Not Applicable

iCorMicA - Stratified Medicine in Angina

Coronary Microvascular Dysfunction (CMD)Angina, StableMicrovascular Angina+1 more
NHS Greater Glasgow and Clyde1,500 enrolled39 locationsNCT04674449
Recruiting

Coronary Flow During Rapid Heart Rates

Heart FailureCoronary Artery DiseaseVentricular Tachycardia+1 more
Imperial College London70 enrolled1 locationNCT05841199
Recruiting

A Study Of CS Reducer For Symptomatic Heart Failure With HFpEF And CMD

Coronary Microvascular DysfunctionHeart Failure With Preserved Ejection Fraction
Mayo Clinic25 enrolled1 locationNCT07093528
Recruiting
Not Applicable

Self-Expanding Coronary Sinus Reducer for Treatment of Symptomatic Coronary Microvascular Dysfunction (CMD) (SERRA-I Study)

Coronary Microvascular Dysfunction
VahatiCor, Inc.30 enrolled2 locationsNCT06991322
Recruiting

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

Kidney TransplantChronic Kidney DiseaseInflammation+1 more
Brigham and Women's Hospital80 enrolled1 locationNCT07222683
Recruiting
Phase 2

Improving Coronary Vascular Health in Women

Metabolic DiseaseHIV-1-infectionCoronary Microvascular Dysfunction
Massachusetts General Hospital80 enrolled1 locationNCT06843902
Recruiting
Phase 4

A Study on the Impact of Bivalirudin Usage During PCI for High-risk Plaques on Post-PCI Coronary Microcirculation.

Coronary Microvascular Dysfunction
Peking University First Hospital70 enrolled1 locationNCT05984537
Recruiting

Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution

Microvascular ObstructionCoronary Microvascular DysfunctionST Elevation Myocardial Infarction
The Cleveland Clinic70 enrolled1 locationNCT06795035
Recruiting

Women's Ischemia Syndrome Evaluation (WISE) Pre-HFpEF

Heart Failure With Preserved Ejection Fraction (HFpEF)Coronary Microvascular Dysfunction
Cedars-Sinai Medical Center180 enrolled2 locationsNCT03876223
Recruiting
Not Applicable

Microvascular Coronary Rehabilitation For Improving Treatment - Feasibility Study

Coronary Microvascular Dysfunction (CMD)Microvascular Coronary DysfunctionMicrovascular Angina
Royal United Hospitals Bath NHS Foundation Trust40 enrolled2 locationsNCT06681896
Recruiting
Phase 4

The Effects of Tirzepatide in People With Overweight/Obesity and Coronary Artery Disease

Stable Angina PectorisCoronary Artery DiseaseCoronary Microvascular Dysfunction+1 more
Tina Vilsbøll124 enrolled3 locationsNCT06606821
Recruiting

INOCA-NA a Local Prospective Registry

Coronary Microvascular Dysfunction (CMD)Non-Obstructive Coronary AtherosclerosisMicrocirculatory Status+1 more
Federico II University250 enrolled1 locationNCT06588244
Recruiting

Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

Myocardial InfarctionCoronary Microvascular DysfunctionVasospasm, Coronary
Chonnam National University Hospital150 enrolled1 locationNCT05272618
Recruiting
Not Applicable

Insulin Resistance and Coronary Microvascular Dysfunction in Patients with Myocardial Ischemia and Non-obstructive Coronary Artery Disease

Coronary Microvascular Dysfunction
Azienda Ospedaliera Universitaria Integrata Verona40 enrolled1 locationNCT06597851
Recruiting

Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease (ANOCA-CMD)

Coronary Microvascular DysfunctionAngina Patients With Non-obstructive Coronary Artery DiseaseIndex of Microvascular Resistance
China-Japan Friendship Hospital100 enrolled1 locationNCT06503640
Recruiting

Coronary Microvascular Disease (CMD) Registry

Coronary Microvascular Dysfunction
Medstar Health Research Institute1,000 enrolled3 locationsNCT05960474
Recruiting

Southeastern Europe Microcirculation Registry

Coronary Artery DiseaseCoronary Microvascular DysfunctionAngina, Microvascular
Institute for Cardiovascular Diseases Dedinje900 enrolled10 locationsNCT06393478
Recruiting
Not Applicable

Study of Microvascular Dysfunction, CFR and Cardioprotective Effect of Early Administration of Esmolol in MI

Myocardial InfarctionCoronary Microvascular DysfunctionCoronary Stenosis
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation300 enrolled1 locationNCT06376630
Recruiting

Belgian Registry on Coronary Function Testing

Coronary Microvascular Dysfunction
University Hospital, Antwerp650 enrolled13 locationsNCT06089031
Recruiting

The role of high power ultrasound in restoring blood flow for patients presenting with a major heart attack.

Microvascular ObstructionHeart FailureCoronary Microvascular Dysfunction+1 more
University of Sydney150 enrolled3 locationsACTRN12620000807954