RecruitingNCT05843604

Cerebral and Cognitive Markers of Treatment Resistance in Obsessive Compulsive Disorder

Cerebral and Cognitive Markers of Treatment Resistance in Obsessive-compulsive Disorder: Towards Personalization of Patient Care

Sponsor

Centre Hospitalier Henri Laborit

Enrollment

100 participants

Start Date

Jul 3, 2023

Study Type

OBSERVATIONAL

Conditions

OCD

Summary

This study aims to define individual profiles of treatment resistants in order to find indicators and predictors of the therapeutic response.

Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria3

Obsessive compulsive disorder diagnosed according to Diagnostic and Statistical Manual 5 criteria (patients will be included regardless of the severity and resistance of their pathology and their levels of executive functions)
Understand and accept the constraints of the study
Be a beneficiary or affiliated to a Health Insurance scheme

Exclusion Criteria6

Present one of the diagnoses according to the criteria of the DSM 5: schizophrenic disorders, substance abuse or dependence to a substance according to the criteria of the M.I.N.I. version 5.0 (Sheehan et al., 1998)
Have a serious intercurrent pathology
Being a pregnant woman
Being a woman of childbearing age without effective contraception.
Being hospitalized under duress or on an outpatient basis in a care program
Being under judicial protection (reinforced curatorship, guardianship)

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Interventions

OTHERFunctional MRI

Three cognitive tests will be performed in the MRI, namely a stroop task, an N-back task and a switching task

Locations(1)

Centre Hospitalier Henri Laborit

Poitiers, France

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NCT05843604

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