RecruitingNot ApplicableNCT05858346

Comparing TBT to Disorder-Specific Psychotherapy in Veterans With Social Anxiety Disorder

A Randomized Clinical Trial Comparing Transdiagnostic Behavior Therapy to Disorder-Specific Psychotherapy in the Recovery of Veterans With Social Anxiety Disorder and Comorbid PTSD Symptomatology


Sponsor

VA Office of Research and Development

Enrollment

264 participants

Start Date

Apr 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Cognitive behavioral therapy (CBT) is a brief, efficient, and effective treatment for individuals with depressive/anxiety disorders. However, CBT is largely underutilized within the Department of Veterans Affairs due to the cost and burden of trainings necessary to deliver all of the related disorder-specific treatments (DSTs). Transdiagnostic Behavior Therapy (TBT), in contrast, is specifically designed to address numerous distinct disorders within a single protocol in Veterans with depressive/anxiety disorders. The proposed research seeks to evaluate the efficacy of TBT by assessing psychiatric symptomatology and related impairment outcomes in Veterans with social anxiety disorder and comorbid posttraumatic stress via a randomized controlled trial of TBT and an existing DST. Assessments will be completed at pre-, mid-, and post-treatment, and at 6-month follow-up. Process variables also will be investigated.


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Inclusion Criteria4

  • Participants must be Veterans and registered at Ralph H. Johnson Veterans Affairs Health Care System
  • Participants must be clearly competent to provide informed consent for research participation
  • Participants must meet DSM-5 criteria for social anxiety disorder
  • Participants must have clinically significant symptoms of comorbid posttraumatic stress

Exclusion Criteria4

  • recent history (\< 2 months) of psychiatric hospitalization or a suicide attempt as documented in their medical record,
  • acute, severe illness or medical condition that likely will interfere with study procedures as documented in their medical record
  • recent start of new psychiatric medication(s) (\< 4 weeks),
  • primary diagnosis of a condition associated with psychotic symptoms, personality disorder, substance use disorder, or bipolar disorder.

Interventions

BEHAVIORALTransdiagnostic Behavior Therapy

TBT was developed to address transdiagnostic avoidance via the use of four different types of exposure techniques (situational/in-vivo, physical/interoceptive, thought/imaginal, and \[positive\] emotional/behavioral activation). From the transdiagnostic avoidance perspective, the four exposure practices are matched to the type(s) of avoidance experienced by patients based upon their cluster of symptoms/disorders.

BEHAVIORALCognitive Behavioral Therapy for Social Anxiety Disorder

To provide an evidence-based comparison for the TBT condition, the research-supported psychological treatment of CBT for SAD will be used. CBT for SAD demonstrates efficacy in improving SAD symptoms and quality of life for patients with SAD, with durable improvements evidenced at follow-up assessments. CBT for SAD was used as a comparison to TBT in previous preliminary research. CBT for SAD involves several primary components, including: 1) psychoeducation, 2) training in cognitive restructuring, 3) exposures, 4) advanced cognitive restructuring, and 5) termination.


Locations(1)

Ralph H. Johnson VA Medical Center, Charleston, SC

Charleston, South Carolina, United States

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NCT05858346


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