RecruitingNot ApplicableNCT05864157

Targeted Motor Learning to Improve Gait for Individuals With Parkinson Disease

Sponsor

University of North Carolina, Chapel Hill

Enrollment

45 participants

Start Date

Aug 16, 2023

Study Type

INTERVENTIONAL

Conditions

Parkinson Disease

Summary

The purpose of this research study is to determine how training to step with a metronome on both a treadmill, as well as overground, will influence the way that people with Parkinson disease walk. Using metronomes is commonly used in clinics, but the investigators will be using a combination of slow and fast frequencies to alter the way that people walk. The use of a slower frequency metronome on the treadmill is intended to help participants take larger steps. The use of a faster frequency metronome while walking overground is intended to help participants take faster steps.This will take place over 12 training sessions. Each session will be about an hour. It will include some walking tests and pictures of the brain (using MRI) before and after training.

Eligibility

Min Age: 50 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study tests a targeted walking training program — using rhythm and treadmill feedback — to improve gait (how you walk) in people with moderate-stage Parkinson's disease who have walking difficulties. **You may be eligible if...** - You are between 50 and 80 years old with a diagnosis of idiopathic Parkinson's disease (Hoehn and Yahr stages 2–3) - You can walk for 10 minutes uninterrupted, both on level ground and on a treadmill - You have noticeable walking problems (shuffling, short steps, freezing, slowed movement) - Your Parkinson's medications (levodopa) have been stable and taken by mouth **You may NOT be eligible if...** - You cannot have an MRI (e.g., metal implants, claustrophobia) - You have significant memory or thinking problems (MoCA score below 26) - You have had deep brain stimulation surgery - You are currently in physical therapy - You have other conditions that affect your walking Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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