RecruitingNCT05868928

Imaging Features for the Risks for Recurrence After Stereotactic Radiosurgery in Brain Metastasis

Imaging Risks for Recurrence After Stereotactic Radiosurgery in Brain Metastasis (IRRAS-BM)

Sponsor

Asan Medical Center

Enrollment

132 participants

Start Date

Dec 7, 2023

Study Type

OBSERVATIONAL

Conditions

Brain Metastases Radiosurgery

Summary

This trial uses multi-parametric magnetic resonance imaging (MRI) to develop and validate imaging risk score to predict radiation necrosis in participants with brain metastasis treated with radiation therapy. Diagnostic procedures, such as multi-parametric magnetic resonance imaging (MRI), may improve the ability to diagnose radiation necrosis early and help establish treatment strategies.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at brain scans taken after stereotactic radiosurgery (a precise, targeted form of radiation) for brain metastases, to identify imaging features that can predict whether the cancer will come back in the same spot. **You may be eligible if...** - You have undergone stereotactic radiosurgery (Gamma Knife or CyberKnife) for brain metastases - You have between one and ten brain metastases - You do not have acute (sudden) neurological symptoms - Your general health score (Karnofsky scale) is 70 or above - You have had a brain MRI within one month of joining the study **You may NOT be eligible if...** - You have more than ten brain metastases - You are experiencing acute neurological problems - You do not have follow-up imaging available for review Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTMagnetic resonance imaging (MRI)

Pre-and post-contrast enhanced T1-weighted image, T2-weighted image, fluid-attenuated inversion recovery image

DIAGNOSTIC_TESTDiffusion-weighted MRI

Diffusion-weighted MRI

DIAGNOSTIC_TESTArterial spin labeling (ASL)

Cerebral blood flow imaging parameter

DIAGNOSTIC_TESTDynamic susceptibility contrast-MRI (DSC-MRI)

Cerebral blood volume and vessel architectural imaging parameters

Locations(1)

Asan Medical Center

Seoul, South Korea

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NCT05868928

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