RecruitingNCT05892952

IONA Longitudinal Cohort Study


Sponsor

Brain Health Scotland Life Sciences Ltd

Enrollment

10,000 participants

Start Date

Dec 21, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Understanding more about how diseases that cause dementia develop is critical as the number of people living with, or affected by, dementia in Scotland continues to grow. The IONA Longitudinal Cohort Study (LCS) has been set up to gather information about people's cognitive health (their memory and thinking abilities), their lifestyle and health risk factors for future dementia (such as hearing loss and obesity), genetics and disease biomarkers, over a number of years. The IONA LCS has three main objectives: Firstly to develop this cohort that is well characterised (also known as being "well-phenotyped") that represent the Scottish population (taking into consideration age, sex, ethnicity and education). The second objective is to use this data to build disease models to better understand trajectories of diseases, and identify any sub-populations who have different (i.e. better, worse) disease trajectories. Finally the third objective for IONA LCS is to offer people an optional consent to hear about future studies they may be interested in taking part in.


Eligibility

Min Age: 50 YearsMax Age: 120 Years

Inclusion Criteria6

  • Age at least 50 years.
  • Living in Scotland.
  • Able to read and write and with minimum 7 years of formal education.
  • Have a study partner who is aged 18 years or older.
  • Have capacity to provide informed consent at baseline.
  • Able to speak English to a level where the cognitive assessments can be completed.

Locations(1)

Scottish Brain Sciences Arran Facility

Edinburgh, Lothian, United Kingdom

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NCT05892952


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