RecruitingNCT05892952

IONA Longitudinal Cohort Study


Sponsor

Brain Health Scotland Life Sciences Ltd

Enrollment

10,000 participants

Start Date

Dec 21, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Understanding more about how diseases that cause dementia develop is critical as the number of people living with, or affected by, dementia in Scotland continues to grow. The IONA Longitudinal Cohort Study (LCS) has been set up to gather information about people's cognitive health (their memory and thinking abilities), their lifestyle and health risk factors for future dementia (such as hearing loss and obesity), genetics and disease biomarkers, over a number of years. The IONA LCS has three main objectives: Firstly to develop this cohort that is well characterised (also known as being "well-phenotyped") that represent the Scottish population (taking into consideration age, sex, ethnicity and education). The second objective is to use this data to build disease models to better understand trajectories of diseases, and identify any sub-populations who have different (i.e. better, worse) disease trajectories. Finally the third objective for IONA LCS is to offer people an optional consent to hear about future studies they may be interested in taking part in.


Eligibility

Min Age: 50 YearsMax Age: 120 Years

Plain Language Summary

Simplified for easier understanding

This long-term study follows people in Scotland aged 50 and above over many years to understand how memory and thinking abilities change with aging and to find early signs of dementia. **You may be eligible if...** - You are at least 50 years old and live in Scotland - You can read and write and have had at least 7 years of formal education - You have a study partner (family member or friend) aged 18 or older who can also participate - You are able to give informed consent **You may NOT be eligible if...** - You are under 50 or do not live in Scotland - You do not have a study partner available - You lack capacity to consent at the start of the study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Scottish Brain Sciences Arran Facility

Edinburgh, Lothian, United Kingdom

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NCT05892952


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