RecruitingNCT05893524

Uppsala-Dalarna Dementia and Gait Project

Sponsor

Dalarna University

Enrollment

550 participants

Start Date

Apr 9, 2015

Study Type

OBSERVATIONAL

Conditions

Dementia Dementia, Mixed Dementia of Alzheimer Type Mild Cognitive Impairment Dementia Senile Subjective Cognitive Impairment

Summary

UDDGait™ is a multidisciplinary research project with the overreaching goal of providing an aid for early identification of cognitive impairment and risk of dementia development, thereby providing a basis for adequate symptom relieving and health promoting interventions. A new concept is investigated for this purpose: a "dual-task-test", which implies the combination of a well-established mobility test (Timed Up-and-Go, TUG) with a simultaneous verbal task (i.e. TUG dual-task, TUGdt). This type of test has been judged as a potential aid for early identification of dementia disease. More research is needed to further examine the test's validity, reliability and predictive capacity. The overall aim is to investigate if TUGdt is useful as an aid for prediction of dementia disease. To ensure the results, the aim is also to evaluate the test's measurement properties and to generate normative reference values of healthy control persons.

Eligibility

Min Age: 37 YearsMax Age: 94 Years

Plain Language Summary

Simplified for easier understanding

This study follows patients undergoing memory assessments at Swedish hospitals to understand how walking patterns (gait) relate to memory problems and dementia risk, comparing people with and without cognitive decline. **You may be eligible if...** - You are undergoing a memory assessment at Uppsala University Hospital or Falun Hospital in Sweden - You have no cognitive impairment (MMSE score above 26) if you are a healthy comparison participant **You may NOT be eligible if...** - You are unable to walk 3 meters back and forth independently - You cannot rise from a seated position without help - You use a walking aid indoors Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTClinical functional assessment

The diagnostic procedure was part of the clinical routine for patients undergoing memory assessment and involved a geriatrician's careful evaluation of the patient's history and cognitive testing including Mini-Mental State Examination (MMSE), Clock Drawing Test, Verbal Fluency Test, and Trail Making Test A and B. In addition, all participants carried out short versions of the Geriatric Depression Scale and the General Motor Function Assessment Scale, as well as static balance according to the Bohannon Method, and hand grip strength using a dynamometer.

DIAGNOSTIC_TESTTimed Up-and-Go (TUG single-task)

The TUG test is a well-established clinical test of one mobility sequence: rising from an armchair, walking straight ahead, passing a line marked on the floor, turning around, walking back, and sitting down again.

DIAGNOSTIC_TESTTimed Up-and-Go dual-task (TUGdt)

Two dual-task tests including TUG (TUGdt) were carried out: TUGdt naming animals and TUGdt months backwards. The outcomes registered were: time scores for TUG single-task and both TUGdt tests, TUGdt costs (relative time difference between TUG single-task and TUGdt), number of different animals named, number of months recited in correct order, number of animals per 10 s, and number of months per 10 s.