RecruitingNot ApplicableNCT05905419

Neuroimaging of Opioid Phase (OPAL)

Neurobiological Consequences of Long-Term Opioid Therapy in the Brain and Spinal Cord

Sponsor

Duke University

Enrollment

140 participants

Start Date

Jun 1, 2023

Study Type

INTERVENTIONAL

Conditions

Opioid Use Chronic Pain

Summary

The purpose of this study is to compare activity in the brains of female adults with chronic pain and/or opioid use, and healthy female adults that may help to develop new and targeted treatments for adults with chronic pain and alternatives to opioid therapy.

Eligibility

Sex: FEMALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Opioid Phase for people with chronic pain and opioid use. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHEROpioid Phase

Opioid-taking patients are assigned to take their prescribed opioid medication before ("peak" opioid phase) during 1 scan and after ("trough" opioid phase) during the other MRI scan