RecruitingNot ApplicableNCT05913882

Combined Respiratory Training in Persons With ALS

Combined Respiratory Training to Improve Pulmonary and Cough Function in Persons With ALS


Sponsor

Nova Southeastern University

Enrollment

34 participants

Start Date

Aug 22, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this interventional trial is to learn about lung volume recruitment (LVR) and expiratory muscle strength training (EMST) in a total of up to 39 patients diagnosed with ALS. The following aims will be addressed: 1. Determine the impact of combined LVR and EMST on cough strength and respiratory function in individuals with ALS. 2. Determine the impact of combined LVR and EMST on patient-reported dyspnea and bulbar impairment. 3. Describe the effect of combined LVR and EMST on patient- and caregiver reported burden and quality of life.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a combined breathing exercise program — both inhaling (lung recruitment) and exhaling (cough strengthening) exercises — in people with ALS (Lou Gehrig's disease) to help protect breathing function and reduce the risk of pneumonia. **You may be eligible if...** - You have a confirmed diagnosis of ALS (probable or definite) - Your ALS symptoms started within the last 2 years - You have not yet used breathing exercise devices - You have a reduced peak cough (below normal for your age and gender) **You may NOT be eligible if...** - Your ALS has progressed to the point that these exercises are unsafe - You already use lung volume recruitment or cough training devices - You use a mechanical ventilator full-time Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICERespiratory Muscle Strength Training (LVR+EMST)

Combined respiratory muscle strength training regimen that will be completed daily for 5 weeks.


Locations(1)

Nova Southeastern University

Fort Lauderdale, Florida, United States

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NCT05913882


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