Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients
A Randomized Controlled Trial of Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients
Rush University Medical Center
250 participants
Jul 10, 2023
INTERVENTIONAL
Conditions
Summary
Around 20% of the obese patients with higher body mass index (BMI) who are taken off the breathing tube and breathing machine (ventilator) end up needing it back to support breathing. The re-application of breathing tube is associated with poor outcomes, including high risk of pneumonia, longer hospital stays, and death. The purpose of this study is to assess if prophylactic use of noninvasive breathing support after removing the breathing tube lowers the chance of needing the breathing tube again.
Eligibility
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Interventions
A total of 24 hours of prophylactic respiratory support will be provided using NIV alternating with HFNC with total NIV usage of 16 hours and HFNC usage of 8 hours.
A total of 24 hours of prophylactic respiratory support will be provided using HFNC alone.
Locations(5)
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NCT05918575