RecruitingNCT05930899

Translational-Omics in Aortic Stenosis (TOmAS) Biobank


Sponsor

McGill University Health Centre/Research Institute of the McGill University Health Centre

Enrollment

10,000 participants

Start Date

Oct 12, 2017

Study Type

OBSERVATIONAL

Conditions

Summary

The objective of the TOmAS Biobank is the conservation of biological material (plasma, saliva, and tissue explanted during surgery), genetic material (DNA, RNA, etc.), and clinical data ("material/data") collected from patients with cardiovascular diseases (CVD) as well as from control participants, in order to allow future studies evaluating novel proteomic, transcriptomic and epigenomic markers (as well as other emerging -omic technologies) for CVD (i.e. aortic stenosis, cardiomyopathy, myorcardial infarction, etc). The study of physiological and genetic factors will allow for the discovery of new genomic and other -omic (including proteomic, transcriptomic and epigenomic) biomarkers associated with CVD which will lead to an improved understanding of the underlying biology of CVD and may provide future insights into the prevention and treatment of this type of disease.


Eligibility

Min Age: 19 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Genetics for people with aortic valve stenosis and cardiovascular diseases. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 19 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERGenetics

TOmAS is a biobank and all patients will be genotyped


Locations(2)

Montreal General Hospital

Montreal, Quebec, Canada

Royal Victoria Hospital

Montreal, Quebec, Canada

View Full Details on ClinicalTrials.gov

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NCT05930899


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