The Efficacy, Mechanism & Safety of Sodium Glucose Co-Transporter-2 Inhibitor & Glucagon-Like Peptide 1 Receptor Agonist Combination Therapy in Kidney Transplant Recipients
A Two Arm, Open Label, Pilot Study to Evaluate the Safety and Efficacy of the Combined Use of Once Daily 10mg Dapagliflozin and Once Weekly 1.0mg Semaglutide in Kidney Transplant Recipients
University Health Network, Toronto
20 participants
Oct 24, 2023
INTERVENTIONAL
Conditions
Summary
The study aims to determine the short-term efficacy, mechanisms and safety of 12 weeks of dapagliflozin and semaglutide combination therapy in 20 KTR, with and without T2D.
Eligibility
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Interventions
Semaglutide subcutaneous once weekly for 12 weeks.
Dapagliflozin oral once daily for 12 weeks.
Locations(1)
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NCT05938712