RecruitingEarly Phase 1NCT05702398

Pilot Trial of Supplemental Vitamin A and Nicotinamide

Pilot Trial of Supplemental Vitamin A and Nicotinamide and Levels of Blood Vitamin A and Nicotinamide


Sponsor

Rhode Island Hospital

Enrollment

30 participants

Start Date

Apr 1, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to assess the feasibility and safety of oral nicotinamide (NAM; a derivative of vitamin B3 \[niacin\]) and vitamin A in a high-risk population of kidney transplant recipients with a history of skin cancer to generate preliminary data for future cancer prevention clinical trials.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Nicotinamide, Other: Placebo, and others for people with kidney transplant recipients and skin cancer. The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGVitamin A

1,000 μg retinyl palmitate twice a day for 6 months

DRUGNicotinamide

500 mg NAM twice a day for 6 months

OTHEROther: Placebo

Identical placebo pills twice a day


Locations(1)

Rhode Island Hospital

Providence, Rhode Island, United States

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NCT05702398


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