RecruitingNot ApplicableNCT05938738

PEP-buddy in COPD: Effect on Dyspnea Severity and Mechanism of Action

A Portable Dyspnea Relief Device for Episodic Breathlessness in COPD (PEP-buddy): Effect on Dyspnea Severity and Mechanism of Action

Sponsor

University Medical Center Groningen

Enrollment

25 participants

Start Date

Jan 31, 2024

Study Type

INTERVENTIONAL

Conditions

COPD

Summary

Chronic dyspnea is the most characteristic symptom of patients with Chronic Obstructive Pulmonary Disease (COPD), with intermittent increases during exercise and other events.Despite optimal standard therapy, episodic dyspnea is a common occurrence in COPD. Recently, the PEP buddy was developed which is an easy-to use, hands-free device that generates positive expiratory pressure (PEP). Although currently the available evidence is limited, it indicates that utilizing the PEP-buddy can result in enhancements in dyspnea during exertion, exertional desaturation and overall quality of life. More research is needed to evaluate the effectiveness of this device and the long term usability, as well as getting more insight in the mechanism of action. Therefore, the aim of our study is to explore the potential of this device for patients with COPD and episodic breathlessness.

Eligibility

Min Age: 40 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a small breathing device called "PEP-buddy" to see if it helps reduce sudden episodes of breathlessness in people with moderate-to-severe COPD (a chronic lung disease). **You may be eligible if...** - You are 40 years of age or older - You have moderate-to-severe COPD (confirmed by breathing tests, with FEV1 less than 60% of predicted) - You regularly experience sudden episodes of breathlessness that require you to stop and rest - Your COPD treatment has already been optimized by your doctor - You have significant COPD symptoms (CAT score of 10 or higher) **You may NOT be eligible if...** - You have other lung conditions that may be causing breathlessness - You are unable to use the device safely - You are currently in a pulmonary rehabilitation program Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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