RecruitingNCT05944692

Epilepsy Seizure Detection With Innovative Tripolar EEG (tEEG)


Sponsor

CREmedical

Enrollment

90 participants

Start Date

Sep 1, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

Concurrent electroencephalography (EEG) and new tripolar EEG (tEEG) will be recorded from adult and pediatric patients. In some patients stereo EEG (sEEG) will also be recorded concurrently.


Eligibility

Min Age: 6 Years

Inclusion Criteria11

  • Pediatric (BCH): Age ≥ 6 years and < 18 years
  • Adult (BNI): Age ≥ 18 years
  • Able to provide written informed consent or have a legally authorized representative able to provide consent; pediatric patients to provide assent when appropriate
  • Scheduled for routine outpatient EEG for clinical diagnosis
  • Able to participate in a post-EEG telemedicine video visit
  • Clinical diagnosis of epilepsy with epileptiform discharges on prior routine EEG
  • Scheduled for inpatient video-EEG monitoring for clinical diagnosis
  • MRI of brain available for co-registration
  • Confirmed diagnosis of focal epilepsy by prior video-EEG monitoring interpreted by board-certified epileptologist or clinical neurophysiologist
  • Scheduled for inpatient video-EEG monitoring with intracranial stereo-EEG electrodes for epilepsy presurgical evaluation
  • MRI of brain available for co-registration

Exclusion Criteria5

  • Presence of a condition or abnormality that in the opinion of the Investigator would compromise the safety of the subject or the integrity of the data
  • Any clinical suspicion of prion disease
  • History of allergy or adverse reaction to EEG electrode paste or gel
  • Scalp lesions or infections
  • Severe intellectual disability or behavioral disorders with inability to cooperate with EEG application or recording

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Interventions

DEVICETripolar electroencephalography

We will record physiological signals with the tripolar electroencephalography


Locations(2)

Barrow Neurological Institute Dignity Health dba St. Joseph's Hospital and Medical Center

Phoenix, Arizona, United States

Boston Children's Hospital

Boston, Massachusetts, United States

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NCT05944692


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