RecruitingNot ApplicableNCT05971875

RCT on 3 Types of Hysterectomy

A Multinational Randomized Controlled Trial Including Two Identical Sub Studies Comparing Vaginal Versus vNOTES (Vaginal Natural Orifice Transluminal Surgery) Hysterectomy or Laparoscopic Versus vNOTES Hysterectomy.


Sponsor

Dr Jan Baekelandt, MD

Enrollment

1,000 participants

Start Date

Jan 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

A randomized controlled trial comparing the vaginal, vNOTES ( vaginal natural orifice transluminal surgery) or laparoscopic approach for hysterectomy in women with benign gynaecological disease


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 75 Years

Inclusion Criteria1

  • • Women aged 18 to 75 years regardless of parity with benign indication for hysterectomy

Exclusion Criteria10

  • Women with a stage II+ prolapse in need of a hysterectomy as part of vaginal prolapse repair
  • hysterectomy due to suspected endometriosis
  • subtotal hysterectomy
  • history of rectal surgery
  • suspected malignancy
  • suspected obliteration of the pouch of Douglas following severe PID or other causes
  • active lower genital tract infection
  • pregnancy
  • failure to provide written informed consent prior to surgery
  • requirement of in-patient care due to other co-morbidities

Interventions

PROCEDUREvNOTES vs Vaginal Hysterectomy

Comparison of vNOTES vs VH

PROCEDUREvNOTES vs Laparoscopic Hysterectomy

Comparison of vNOTES vs LH


Locations(2)

Dept of Obstetrics and Gynecology

Zadar, Croatia

Dept of Obstetrics and Gynecology

Helsingborg, Sweden

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05971875


Related Trials