RecruitingNot ApplicableNCT06939023

Laparoscopic Versus Robot-assisted Left-sided Pancreatectomy for Benign and Pre-malignant Lesions (DIPLOMA-3)

Laparoscopic Versus Robot-assisted Left-sided Pancreatectomy for Benign and Pre-malignant Lesions (DIPLOMA-3): an International Multicenter Patient-blinded Randomized Controlled Trial


Sponsor

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Enrollment

256 participants

Start Date

Jun 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The DIPLOMA-3 trial is an international, multicenter, patient-blinded randomized controlled trial comparing laparoscopic and robot-assisted left-sided pancreatectomy. Patients with an indication for elective left-sided pancreatecomy for benign or premalignant lesions in the body or tail of the pancreas and considered eligible will be randomized between laparoscopic and robot-assisted resection.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two minimally invasive surgical approaches for removing part of the pancreas: traditional laparoscopic surgery (using a camera and small instruments) versus robot-assisted surgery. The operation is for benign or pre-cancerous conditions on the left side of the pancreas. Researchers want to know which approach leads to better outcomes. **You may be eligible if...** - You are 18 or older - You need elective surgery to remove part of the left side of your pancreas due to a benign or pre-cancerous condition - Both laparoscopic and robotic approaches are technically feasible for your case - You are fit for surgery as assessed by your surgical team **You may NOT be eligible if...** - Your tumor is suspected to be pancreatic ductal adenocarcinoma (the most common and aggressive form of pancreatic cancer) - Your cyst or tumor is larger than 8 cm - Surgery would require removing other organs besides the pancreas and spleen - Your tumor involves or is touching major blood vessels - You are pregnant or have a BMI over 40 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

PROCEDURELaparoscopic minimally invasive left-sided pancreatecomy

Laparoscopic minimally invasive left-sided pancreatecomy

PROCEDURERobot-assisted minimally invasive left-sided pancreatecomy

Robot-assisted minimally invasive left-sided pancreatecomy


Locations(1)

Amsterdam UMC

Amsterdam, Netherlands

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06939023


Related Trials