Robot-assisted Versus Open Lateral Pancreaticojejunostomy for the Treatment of Symptomatic Chronic Pancreatitis (PANACOTTA)
Robot-assisted Versus Open Lateral Pancreaticojejunostomy for the Treatment of Symptomatic Chronic Pancreatitis (PANACOTTA): a Multicenter Randomized Controlled Trial
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
28 participants
Apr 16, 2025
INTERVENTIONAL
Conditions
Summary
PANACOTTA is a multicenter randomized controlled trial including patients with symptomatic chronic pancreatitis and a dilated main pancreatic duct to either robot-assisted or open lateral pancreaticojejunostomy. The PANACOTTA trial will assess the post-operative quality of recovery following robot-assisted versus open lateral pancreaticojejunostomy.
Eligibility
Inclusion Criteria5
- At least 18 years old
- Indication for (extended or partial) lateral pancreaticojejunostomy as agreed during multidisciplinary team meeting based on symptomatic chronic pancreatitis (i.e. morphine dependent pain or recurrent acute flares of pancreatitis, at least 3 episodes per year) and a dilated pancreatic duct of ≥ 5 mm, with a non-enlarged pancreatic head \< 40 mm
- Confirmed CP, according to the M-ANNHEIM diagnostic Criteria24
- Eligible for both an robot-assisted and open approach
- Obtained written informed consent
Exclusion Criteria5
- Suspected or confirmed current pancreatic cancer
- ASA classification ≥ 4
- Other painful conditions aside from CP, with pain difficult to discriminate from CP pain
- Prior pancreatic surgery
- Pregnancy
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Interventions
Robot-assisted
Open surgery
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT07109180