RecruitingNot ApplicableNCT05977803
Contribution of the CEST Sequence in the Characterization of Radionecrosis of Brain Metastases of Pulmonary Origin
Sponsor
Assistance Publique - Hôpitaux de Paris
Enrollment
60 participants
Start Date
Feb 15, 2024
Study Type
INTERVENTIONAL
Conditions
Summary
The aim of the study is to determine whether the use of the CEST sequence would have diagnostic performance equivalent to the reference method of T2\* infusion with contrast injection in the diagnosis of radionecrosis of lung cancer brain metastases.
Eligibility
Min Age: 18 Years
Inclusion Criteria7
- Patients \> 18 years of age
- Histologically proven primary lung cancer
- Histologically proven or not brain metastases
- Irradiated metastases
- Inclusion in a treatment protocol for brain metastases by brain metastasis in toto or stereotactic or gamma-knife radiotherapy
- Morphological increase of one or more lesions of secondary brain metastases on a follow-up MRI
- Patients affiliated to a social security scheme
Exclusion Criteria6
- Opposition to the study
- Contraindication to MRI
- Refusal of imaging by the patient
- Patient with state medical aid (unless exemption from affiliation)
- Severe cognitive impairment making informed consent impossible
- Patients under guardianship or deprived of liberty
Interventions
RADIATIONMRI with CEST sequence, IVIM and ASL sequence
Three sequences will be added as part of the protocol (for an additional duration of about 10 minutes) : * The CEST sequence * The ASL infusion sequence * The IVIM sequence
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT05977803
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