Breathing Rescue for SUDEP Prevention
Breathing Rescue for SUDEP Prevention (BreatheS)
The University of Texas Health Science Center, Houston
100 participants
Jul 31, 2023
INTERVENTIONAL
Conditions
Summary
The purpose of this study is to precisely delineate human brain networks that modulate respiration and identify specific brain areas and stimulation techniques that can be used to prevent seizure-induced breathing failure.
Eligibility
Inclusion Criteria2
- diagnosis of intractable focal epilepsy
- admitted to the Epilepsy Monitoring Unit (EMU) at Memorial Hermann-Texas Medical Center for intracranial subdural strips, grids, or depth electrode placement study (invasive video-EEG)
Exclusion Criteria3
- respiratory, cardiac or cerebrovascular disease
- pregnancy
- prisoners
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Interventions
Breathing tasks include normal breathing through nose or mouth, breathing while resting wakefully, increase and decrease in breathing rate, and breath counting.
Electrical stimulation will be used to find specific areas of the brain involved in breathing function. Stimulation will be applied using a Nihon Kohden MEE-1000A neural function measuring system with the MS-120BK extension unit for brain stimulation.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05981755