Safety and Efficacy of Botulinum Toxin A for Treatment of Overactive Bladder in Parkinson's Disease

This study is testing Botox (botulinum toxin A) injected into the bladder to treat overactive bladder (a condition causing urgency, frequent urination, and sometimes leakage) in people with Parkinson's disease. **You may be eligible if...** - You have idiopathic Parkinson's disease (the most common form, not caused by another condition) - You have overactive bladder symptoms, confirmed by a 3-day voiding diary and scoring questionnaire - You are between 25 and 80 years old - You are currently taking dopaminergic medications for Parkinson's **You may NOT be eligible if...** - You have a different form of Parkinson's (not idiopathic) - You do not have overactive bladder symptoms confirmed by assessment - You are outside the 25–80 age range - You are unable to tolerate the evaluation required for inclusion Talk to your doctor to see if this trial is right for you.