Overactive Bladder Clinical Trials

33 recruiting

Overactive Bladder Trials at a Glance

54 actively recruiting trials for overactive bladder are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 33 trials, with the heaviest enrollment activity in Chicago, Palo Alto, and Houston. Lead sponsors running overactive bladder studies include Walter Reed National Military Medical Center, Axonics, Inc., and Ege University.

Browse overactive bladder trials by phase

Treatments under study

About Overactive Bladder Clinical Trials

Looking for clinical trials for Overactive Bladder? There are currently 33 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Overactive Bladder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Overactive Bladder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 54 trials

Recruiting
Phase 2Phase 3

Examining the Effects of Intra-detrusor Botox at Time of HoLEP in Men With Overactive Bladder Symptoms

Urinary IncontinenceOveractive BladderUrologic Diseases+1 more
Northwestern University66 enrolled1 locationNCT05878951
Recruiting
Not Applicable

Evaluating Pumpkin Seed Oil Extract Supplementation on Bladder Function

Overactive Bladder (OAB)
Northwestern University40 enrolled1 locationNCT06944392
Recruiting
Not Applicable

Vitamin D Treat-to-Target Strategy for Children With Overactive Bladder-Wet

Overactive BladderUrinary Bladder, OveractiveUrinary Incontinence, Urge
Children's Hospital of Chongqing Medical University180 enrolled1 locationNCT06201013
Recruiting
Not Applicable

Sacral Neuromodulation for Male Overactive Bladder (MOAB)

Prostate CancerProstatectomyBenign Prostatic Hyperplasia+3 more
Axonics, Inc.150 enrolled20 locationsNCT06511141
Recruiting
Not Applicable

PMCF Study of the Axonics SNM System Model 5101 (R20) for the Indication of OAB

Overactive Bladder (OAB)Urinary Urge Incontinence (UUI)Urinary Frequency (UF)
Axonics, Inc.55 enrolled4 locationsNCT06789406
Recruiting
Not Applicable

Impact of TTNS on Bladder Symptoms Among People With MS, A RCT

Overactive Bladder Syndrome
Hawra Al-Dandan72 enrolled1 locationNCT06341673
Recruiting

Noninvasive Ultrasound Assessment of Detrusor Dysfunction

Overactive BladderBladder DysfunctionBPH With Urinary Obstruction
Mayo Clinic2,023 enrolled1 locationNCT05652023
Recruiting
Not Applicable

Neuromodulating Cortical Regions Involved in Neurogenic Bladder in MS

Multiple SclerosisOveractive BladderNeurogenic Bladder
The Methodist Hospital Research Institute29 enrolled1 locationNCT06072703
Recruiting
Phase 4

Low-intensity Shockwave Therapy Versus Solifenacin for the Treatment of Overactive Bladder in Women

Overactive Bladder (OAB)
Mansoura University70 enrolled1 locationNCT07473310
Recruiting
Phase 4

TReating Incontinence for Underlying Mental and Physical Health

IncontinenceUrinary IncontinenceOveractive Bladder+3 more
University of California, San Francisco270 enrolled2 locationsNCT05362292
Recruiting
Not Applicable

Clinical and Urodynamic Assessment of Bladder Sensation in Multiple Sclerosis

Overactive Bladder
Assistance Publique - Hôpitaux de Paris113 enrolled1 locationNCT05772637
Recruiting
Not Applicable

Fluoroscopy Radiation Reduction During Sacral Neuromodulation Lead Placement

Radiation ExposureOveractive Bladder
Loma Linda University44 enrolled1 locationNCT04527445
Recruiting
Not Applicable

Pelvic Health Electrically Evoked Recording (PEER) 2 Study

Urinary RetentionOveractive BladderFecal Incontinence
MedtronicNeuro300 enrolled7 locationsNCT05200923
Recruiting
Phase 2

Zinc Supplementation With Botulinum Toxin for Overactive Bladder

Overactive Bladder (OAB)
Endeavor Health72 enrolled1 locationNCT07405554
Recruiting
Not Applicable

Add-On ZIDA Sock Therapy for Overactive Bladder

Overactive Bladder
Medical University of South Carolina20 enrolled1 locationNCT07432659
Recruiting
Phase 4

Randomized Controlled Trial Comparing Low Dose Tadalafil Versus Solifenacin For Management of Overactive Bladder in Women: Multicenter Egyptian National Study

Overactive Bladder (OAB)Overactive Bladder Syndrome
Mansoura University480 enrolled14 locationsNCT07416968
Recruiting
Not Applicable

INOPASE - Performance and Safety Study of a Personalised SNM System

Overactive Bladder (OAB)
INOPASE Pty Ltd10 enrolled2 locationsNCT07193407
Recruiting
Not Applicable

Evaluation of a Non-Implanted Electrical Stimulation Device for Overactive Bladder (OAB)

Overactive Bladder (OAB)
FemPulse Corporation151 enrolled15 locationsNCT07195656
Recruiting
Not Applicable

Yoga for Treatment of Overactive Bladder in Pediatric Patients

Overactive BladderOveractive Bladder SyndromeOveractive Detrusor
Duke University40 enrolled1 locationNCT05895045
Recruiting
Not Applicable

Detrusor Nerve Radiofrequency Ablation for Overactive Bladder in Women

Overactive BladderOveractive Bladder (OAB)Urge Urinary Incontinence+1 more
InMode MD Ltd.202 enrolled9 locationsNCT07209397