RecruitingNCT06001073

Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics

Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics (PROSPECT): a National, Multicenter, Retrospective-prospective, Cohort Study

Sponsor

First Affiliated Hospital Xi'an Jiaotong University

Enrollment

25,000 participants

Start Date

Dec 5, 2022

Study Type

OBSERVATIONAL

Conditions

Cardiomyopathies Brain Neoplasms Hypertension Arrhythmias, Cardiac Coronary Artery Disease Heart Valve Diseases Aortic Dissection Heart Neoplasms Myocarditis Structural Heart Disease Ischemic Cerebrovascular Disease Hemorrhagic Cerebrovascular Disease

Summary

The etiology and specific pathogenesis of many cardiovascular diseases such as coronary atherosclerosis, cardiomyopathy, atrial fibrillation, and stroke are still unclear. Improving diagnosis and treatment, clarifying the pathogenesis, and providing scientific basis for the prevention and treatment are hot research topics in the study of cardiovascular and cerebrovascular diseases. This study intends to collect clinical data and biological specimen data of patients with cardiovascular and cerebrovascular diseases who meet the inclusion and exclusion criteria, and use multi-omics technology to deeply understand the pathogenic mechanisms of cardiovascular and cerebrovascular diseases and provide new ideas for specific and individualized treatment of patients with cardiovascular and cerebrovascular diseases, to construct early predictive prognostic models and provide a basis for effective treatment of clinical practice in patients with cardiovascular and cerebrovascular diseases.

Eligibility

Min Age: 3 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This observational study collects blood, tissue, and other biological samples from patients with a range of heart and brain blood vessel diseases to build a large database of multi-level biological data (called multi-omics) to improve disease prognosis prediction. **You may be eligible if...** - You are between 3 and 80 years old - You are regularly seen and followed up at the study hospital - You have been diagnosed with one or more cardiovascular or cerebrovascular conditions, including coronary artery disease, arrhythmia, heart valve disease, aortic dissection, cardiomyopathy, hypertension, structural heart disease, ischemic stroke, brain hemorrhage, or intracranial tumors **You may NOT be eligible if...** - You are under 3 or over 80 years old - You are pregnant or breastfeeding - You declined to provide informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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