Brain Neoplasms Clinical Trials

22 recruitingLast updated: June 17, 2026

There are 22 actively recruiting brain neoplasms clinical trials across 21 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3. Top locations include Boston, Massachusetts, United States, London, United Kingdom, New York, New York, United States. Updated daily from ClinicalTrials.gov.


Brain Neoplasms Trials at a Glance

22 actively recruiting trials for brain neoplasms are listed on ClinicalTrialsFinder across 6 cities in 21 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Boston, London, and New York. Lead sponsors running brain neoplasms studies include Jasper Gerritsen, Dartmouth-Hitchcock Medical Center, and Cancer Research UK.

Browse brain neoplasms trials by phase

Treatments under study

About Brain Neoplasms Clinical Trials

Looking for clinical trials for Brain Neoplasms? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Brain Neoplasms trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Brain Neoplasms clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 22 trials

Recruiting
Phase 1

A Study to Learn About the Study Medicine Called PF-07799544 as Monotherapy or in Combination in People With Advanced Solid Tumors

MelanomaNon-small Cell Lung CancerThyroid Cancer+10 more
Pfizer124 enrolled82 locationsNCT05538130
Recruiting
Phase 1Phase 2

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting
Not Applicable

The Effect of Education Brain Tumors

Primary Brain Neoplasms
Istanbul University - Cerrahpasa72 enrolled1 locationNCT07617168
Recruiting
Phase 3

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled95 locationsNCT06388733
Recruiting
Not Applicable

Guided Meditation During Radiation Therapy for Brain Tumors

Brain Neoplasms
University of Utah30 enrolled1 locationNCT06165653
Recruiting
Not Applicable

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

Brain Neoplasms
Mayo Clinic20 enrolled1 locationNCT06322602
Recruiting
Not Applicable

OT SMILE: Occupational Therapy Group Intervention for Primary Brain Tumour Patients

Brain NeoplasmsGlioblastomaPrimary Brain Tumour
Royal College of Surgeons, Ireland96 enrolled1 locationNCT07426848
Recruiting

Detection of Brain Metastases Using a Novel Gadolinium-Weighted MRI Sequence: A Prospective Comparison

Brain Neoplasms
Region Stockholm100 enrolled1 locationNCT07272616
Recruiting
Not Applicable

Platelets Activation in Brain Neoplasms

Brain NeoplasmsGliomaInflammation+1 more
Fondation Ophtalmologique Adolphe de Rothschild50 enrolled1 locationNCT05049148
Recruiting
Phase 1

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca180 enrolled12 locationsNCT03423628
Recruiting
Phase 2Phase 3

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.

MalignancyMelanomaCancer+8 more
Cancer Research UK30 enrolled27 locationsNCT05770544
Recruiting
Not Applicable

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

Brain NeoplasmsBrain TumorCognitive Dysfunction+9 more
Dartmouth-Hitchcock Medical Center125 enrolled1 locationNCT06930846
Recruiting
Not Applicable

Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery

Brain Neoplasms
University of Illinois at Chicago8 enrolled1 locationNCT07111182
Recruiting
Phase 1

Phase I Study of JYP0322 in ROS1 Fusion-Positive Solid Tumors

Lung NeoplasmsBrain NeoplasmsProtein Kinase Inhibitors+1 more
Guangzhou JOYO Pharma Co., Ltd101 enrolled1 locationNCT06128148
Recruiting

Diagnostic Assessment of Amino Acid PET/MRI in the Evaluation of Glioma and Brain Metastases

Brain Neoplasms
Norwegian University of Science and Technology160 enrolled3 locationsNCT04111588
Recruiting

Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics

CardiomyopathiesBrain NeoplasmsHypertension+9 more
First Affiliated Hospital Xi'an Jiaotong University25,000 enrolled1 locationNCT06001073
Recruiting

Experiences and Needs of Patients With a High-grade Glioma and Their Caregivers

Brain Neoplasms, Primary Malignant
Universitaire Ziekenhuizen KU Leuven30 enrolled1 locationNCT01638130
Recruiting
Phase 2

SGM-101 in Colorectal Brain Metastases.

Colorectal NeoplasmsGastrointestinal CancerBrain Metastases+10 more
Leiden University Medical Center10 enrolled2 locationsNCT04755920
Recruiting

The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201)

Brain NeoplasmsGlioblastomaGlioblastoma, IDH-wildtype+9 more
Jasper Gerritsen784 enrolled8 locationsNCT06118723
Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

Brain NeoplasmsGlioblastomaGlioblastoma, IDH-wildtype+6 more
Erasmus Medical Center225 enrolled8 locationsNCT06273176