Brain Neoplasms Clinical Trials

15 recruiting

Brain Neoplasms Trials at a Glance

19 actively recruiting trials for brain neoplasms are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in London, Boston, and Glasgow. Lead sponsors running brain neoplasms studies include Cancer Research UK, Dartmouth-Hitchcock Medical Center, and AstraZeneca.

Browse brain neoplasms trials by phase

Treatments under study

About Brain Neoplasms Clinical Trials

Looking for clinical trials for Brain Neoplasms? There are currently 15 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Brain Neoplasms trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Brain Neoplasms clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Phase 1Phase 2

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting
Phase 3

A Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated Glioblastoma

Brain TumorGlioblastomaGBM+1 more
Ivy Brain Tumor Center450 enrolled95 locationsNCT06388733
Recruiting
Not Applicable

Guided Meditation During Radiation Therapy for Brain Tumors

Brain Neoplasms
University of Utah30 enrolled1 locationNCT06165653
Recruiting
Not Applicable

Ommaya Reservoir Placement at the Time of Biopsy for Longitudinal Biomarker Collection in Patients With Brain Tumors

Brain Neoplasms
Mayo Clinic20 enrolled1 locationNCT06322602
Recruiting
Not Applicable

OT SMILE: Occupational Therapy Group Intervention for Primary Brain Tumour Patients

Brain NeoplasmsGlioblastomaPrimary Brain Tumour
Royal College of Surgeons, Ireland96 enrolled1 locationNCT07426848
Recruiting

Detection of Brain Metastases Using a Novel Gadolinium-Weighted MRI Sequence: A Prospective Comparison

Brain Neoplasms
Region Stockholm100 enrolled1 locationNCT07272616
Recruiting
Not Applicable

Platelets Activation in Brain Neoplasms

Brain NeoplasmsGliomaInflammation+1 more
Fondation Ophtalmologique Adolphe de Rothschild50 enrolled1 locationNCT05049148
Recruiting
Phase 1

A Study to Assess the Safety and Tolerability of AZD1390 Given With Radiation Therapy in Patients With Brain Cancer

Recurrent Glioblastoma MultiformePrimary Glioblastoma MultiformeBrain Neoplasms, Malignant+1 more
AstraZeneca180 enrolled12 locationsNCT03423628
Recruiting
Phase 2Phase 3

DETERMINE Trial Treatment Arm 03: Entrectinib in Adult, Paediatric and Teenage/Young Adult Patients With ROS1 Gene Fusion-Positive Cancers.

MalignancyMelanomaCancer+8 more
Cancer Research UK30 enrolled27 locationsNCT05770544
Recruiting
Not Applicable

HOBSCOTCH-CA (HOme-Based Self-management and COgnitive Training CHanges Lives in Brain CAncer)

Brain NeoplasmsBrain TumorCognitive Dysfunction+9 more
Dartmouth-Hitchcock Medical Center125 enrolled1 locationNCT06930846
Recruiting
Not Applicable

Intraoperative Fluorescence-Guided Aspirate Tissue Monitoring of 5-ALA During Brain Tumor Surgery

Brain Neoplasms
University of Illinois at Chicago8 enrolled1 locationNCT07111182
Recruiting
Phase 1

Phase I Study of JYP0322 in ROS1 Fusion-Positive Solid Tumors

Lung NeoplasmsBrain NeoplasmsProtein Kinase Inhibitors+1 more
Guangzhou JOYO Pharma Co., Ltd101 enrolled1 locationNCT06128148
Recruiting

Diagnostic Assessment of Amino Acid PET/MRI in the Evaluation of Glioma and Brain Metastases

Brain Neoplasms
Norwegian University of Science and Technology160 enrolled3 locationsNCT04111588
Recruiting

Prognosis Prediction System of Patients With Cardiovascular and Cerebrovascular Diseases Based on Multi-omics

CardiomyopathiesBrain NeoplasmsHypertension+9 more
First Affiliated Hospital Xi'an Jiaotong University25,000 enrolled1 locationNCT06001073
Recruiting

Experiences and Needs of Patients With a High-grade Glioma and Their Caregivers

Brain Neoplasms, Primary Malignant
Universitaire Ziekenhuizen KU Leuven30 enrolled1 locationNCT01638130
Recruiting
Phase 2

SGM-101 in Colorectal Brain Metastases.

Colorectal NeoplasmsGastrointestinal CancerBrain Metastases+10 more
Leiden University Medical Center10 enrolled2 locationsNCT04755920
Recruiting

The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma

Brain NeoplasmsGlioblastomaGlioblastoma, IDH-wildtype+6 more
Erasmus Medical Center225 enrolled8 locationsNCT06273176
Recruiting
Not Applicable

The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients.

Brain NeoplasmsBrain TumorBrain Cancer+4 more
Jasper Gerritsen246 enrolled5 locationsNCT03861299
Recruiting

The Cohort for Patient-reported Outcomes, Imaging and Trial Inclusion in Metastatic BRAin Disease (COIMBRA)

Brain Metastases, AdultBrain Neoplasms, Adult, Malignant
UMC Utrecht1,000 enrolled1 locationNCT05267158