Microneedling With Regular Insulin Versus Microneedling Alone in Treatment of Atrophic Scars
Alexandria University
40 participants
Oct 1, 2023
INTERVENTIONAL
Conditions
Summary
Recently, few studies have attempted to test the regenerative effects of human insulin application by microneedling on atrophic scars versus other topical preparations. However, the scars were limited etiologically to acne scars. In addition, a lack of inclusion of a control group instead of comparing topical preparations with insulin was also a limitation to these studies. A control group consisting of microneedling alone would have served as a better comparison in order to determine whether the effects of microneedling are augmented by topical protein-rich preparations.
Eligibility
Inclusion Criteria3
- Patients aged 12 to 60 years
- Atrophic scars (traumatic or surgical)
- Completely healed scars
Exclusion Criteria6
- Patients with a tendency or history of hypertrophic or keloidal scars
- Patients who received treatment for their scar in the past 3 months
- Diabetic patients or those with a history of Dysglycemia
- Pregnant, or lactating females
- Patients with active infection at the site of scar
- Patients currently receiving isotretinoin treatment or in the past month
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Interventions
Microneeling preformed onto the scar In one group insulin will be applied while saline will be used in the second group
Microneeling preformed onto the scar In one group insulin will be applied while saline will be used in the second group
Locations(1)
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NCT06021275